具备常规起搏治疗适应症的心力衰竭合并心房颤动的心脏再同步化治疗  

CARDIAC RESYNCHRONIZATION THERAPY ON PATIENTS WITH HEART FAILURE AND CONCOMITANT ATRIAL FIBRILLATION SUITABLE FOR CONVENTIONAL PACING THERAPY

作　　者：刘君[1] 靳文[1] 李冬义[1] 杜作义[1] 

机构地区：[1]广东省第二人民医院,广东广州510317

出　　处：《现代医院》2015年第8期34-35,38,共3页Modern Hospitals

基　　金：广东省科技计划项目(编号:2012B061700025);广东省自然科学基金(编号:S2012040006782)

摘　　要：目的：探讨具备常规起搏治疗适应症的心力衰竭合并心房颤动患者行心脏再同步化治疗的短期疗效。方法收集2008年1月∽2013年1月具备常规起搏治疗适应症的心力衰竭合并心房颤动的患者12例，行心脏再同步化治疗，治疗前以及治疗后的3、6、12个月分别测量6分钟步行实验（6MWT）、左室舒张末内径（LVEDD）、左室射血分数（LVEF）和心排血量（CO），并用SPSS18．0作统计分析。结果12例患者三腔起搏器各电极植入过程顺利，手术成功，起搏器工作良好，无手术相关并发症。术后第3、第6、第12个月的6MWT、LVEDD、LVEF和CO指标较术前各指标均有明显改善，差异有统计学意义（p＜0.05），且随时间的延长心功能指标持续性优化。结论心脏再同步化治疗短期内可有效改善心力衰竭合并心房颤动患者的心功能水平。Objective To discuss the short-term effect of Cardiac Resynchronization Therapy （ CRT） on patients with heart failure and concomitant atrial fibrillation suitable for conventional pacing therapy .Methods 12 patients with heart failure and con-comitant atrial fibrillation suitable for conventional pacing therapy were treated with CRT in our hospital , and their cardiac parameters such as 6 minutes walk test （6MWT）, left ventrieular end -diastolic diameter （LVDD）, left ventrieular ejection fraction （LVEF） and cardiac output （CO） were measured before operation and 3, 6 and 12 months after operation respectively.Finally the measured data was analyzed with SPSS 18.0.Results All electrodes of three -chamber pacemaker were implanted successfully without any complication.Compared with those at baseline, the four heart function parameters of the 12 patients at three, six, twelve months after CRT were improved significantly and successively （p〈0.05）.Conclusion CRT can help the patients with heart failure and con-comitant atrial fibrillation to improve their heart function effectively and successively in the short term .

关 键 词：心力衰竭 心房颤动 心脏再同步化治疗 

分 类 号：R541.62[医药卫生—心血管疾病]