持续负压封闭引流技术治疗感染性糖尿病足的临床效果  

Clinical effect of continued vacuum sealing drainage in the treatment of infective diabetic foot

作　　者：李惠贤[1] 陈幼萍[1] 舒毅[1] 曾春平[1] 梁蕴谊[1] 

机构地区：[1]广东省佛山市南海区人民医院,广东佛山528200

出　　处：《中国医药导报》2015年第22期82-84,88,共4页China Medical Herald

基　　金：广东省佛山市卫生和计划生育局医学科研课题(2014234)

摘　　要：目的 探讨持续负压封闭引流（VSD）技术治疗感染性糖尿病足的临床效果。方法 选取广东省佛山市南海区人民医院2012年8月-2013年8月收治的52例糖尿病足患者为研究对象,分为对照组与观察组。两组患者首先均接受糖尿病教育、注射胰岛素降低血糖以及糖尿病饮食等常规治疗方法。在此基础上观察组使用持续VSD进行治疗,对照组患者采用降纤酶治疗。比较两组患者的足部动脉血流速度、运动神经传导速度（MCV）、感觉神经传导速度（SCV）以及治疗效果。结果 两组患者治疗后,足部动脉血流速度均较治疗前明显改善,治疗后观察组显著优于对照组,差异有统计学意义（P〈0.05）。两组患者治疗前MCV、SCV比较,差异无统计学意义（P〉0.05）,治疗后观察组MCV、SCV显著优于对照组,差异有统计学意义（P〈0.05）。观察组患者的治疗有效率明显高于对照组,差异有统计学意义（P〈0.05）。结论 与降纤酶相比,应用持续VSD技术治疗糖尿病足可以更好地促进患者足部溃疡的愈合,具有较好效果,值得临床应用与推广。Objective To discuss the clinical effect of continued vacuum sealing drainage in the treatment of infective diabetic foot. Methods 52 cases of patients with diabetic foot were selected in Nanhai District People＇s Hospital of Foshan City from August 2012 to August 2013 as research objects. Patients were divided into the control group and observation group. Two groups of patients were all given conventional treatment, including diabetes education, injection of insulin to reduce blood sugar, diabetic diet and so on. On the basis of the conventional treatment, patients in the observation group were treated with continued vacuum sealing drainage, while patients in the control group were given defibrase therapy. Foot artery blood flow velocity, MCV, SCV and therapeutic effect of the two groups were compared. Results After treatment, the foot artery blood flow velocity of the two groups were all significantly improved than before treatment, which in the observation group was significantly better than the control group, with statistically significant differences（P〈0.05）. Before treatment, MCV and SCV had no significant difference between the two groups（P〉0.05）,but after treatment, MCV and SCV of the observation group was significantly better than those of the control group, with statistically significant differences（P〈0.05）. The treatment effective rate of the observation group was significantly higher than that of the control group, with statistically significant difference（P〈0.05）. Conclusion Compared with defibrase, application of continued vacuum sealing drainage in the treatment of infective diabetic foot can better promote the healing of foot ulcers, has a good effect, which is worthy of clinical application and promotion.

关 键 词：负压封闭引流 糖尿病足 降纤酶 血液流变学 

分 类 号：R587.2[医药卫生—内分泌]