^(18)F-脱氧葡萄糖PET-CT与腹部增强CT检查对腹膜转移瘤的诊断价值  

Diagnostic value of ^(18)F-FDG PET-CT and abdomen enhancement CT in peritoneal metastasis

作　　者：韩建国[1] 任道凌[1] 韩明山[2] 

机构地区：[1]山东省泰安市中心医院核医学科,山东泰安271023 [2]山东省泰安市中心医院放射科,山东泰安271023

出　　处：《中国医药导报》2015年第22期132-135,F0003,共5页China Medical Herald

摘　　要：目的比较~18F脱氧葡萄糖(~18F-FDG)PET-CT和腹部增强CT在腹膜转移瘤诊断中的临床价值。方法对泰安市中心医院2011年10月~2015年1月收治的109例怀疑腹膜转移瘤的患者进行~18F-FDG PET-CT和腹部增强CT检查,通过病理检查和临床随访相互印证的方式证实患者确实存在腹膜转移瘤,比较两种方法在腹膜转移瘤诊断上的临床价值。结果 85例出现了腹膜转移,24例未出现腹膜转移。PET-CT对诊断腹膜转移瘤的特异度为79.2%(19/24),敏感度为92.9%(79/85),准确性为89.9%(98/109),其中有3例假阳性和8例假阴性;腹部增强CT诊断腹膜转移瘤的特异度为70.8%(17/24),敏感度为67.1%(57/85),准确性为67.9%(74/109),其中有5例假阳性和30例假阴性。两种方法的诊断准确率比较差异有高度统计学意义(χ~2=9.196,P=0.002)。结论 ~18F-FDG PETCT在腹膜转移瘤诊断上的临床价值明显高于腹部增强CT。Objective To compare diagnostic value of 18F-FDG PET-CT and abdomen enhancement CT in peritoneal metastasis. Methods From October 2011 to January 2015, 109 patients suspected peritoneal metastases in the Central Hospital of Tai＆#39;an were admitted to 18F-FDG PET-CT and abdominal CT examination. Clinical value in the diagnosis of peritoneal metastases of the two methods were compared. Final diagnosis was made by pathology and clinical follow-up. Results 85 patients were confirmed peritoneal metastases after pathological examination and clinical follow-up, while the other 24 patients were absent. The sensitivity of 18F-FDG PET-CT was 92.9% （79/85）, the specificity was 79.2%（19/24）, and the accuracy was 89.9% （98/109）. There were 3 cases of false positive and 8 cases of false negative. The sensitivity of abdomen enhancement CT was 67.1% （57/85）, the specificity was 70.8% （17/24）, and the accuracy was 67.9%（74/109）. There were 5 false positive cases and 30 false negative cases. The difference between the two methods was statistically significantly （χ^2=9.196, P=0.002）. Conclusion The diagnostic value of 18F-FDG PET-CT is significant-ly higher than that of abdomen enhancement CT for peritoneal metastasis staging analysis.

关 键 词：恶性肿瘤 腹膜转移 ^18F-FDG PET-CT 腹部增强CT 诊断 

分 类 号：R814.42[医药卫生—影像医学与核医学]