剪切波弹性成像定量测量活体血栓弹性的实验研究  

Quantitative evaluation of the thrombosis elasticity in vivo by shear wave elastography

作　　者：袁宇[1] 朱鹰[2] 高金妹[1] 刘蒙[3] 尹蔚芳 

机构地区：[1]天津市天津医院超声科,300211 [2]天津医科大学附属肿瘤医院乳腺影像科 [3]天津市天津医院超血管外科,300211

出　　处：《中华超声影像学杂志》2015年第7期615-617,共3页Chinese Journal of Ultrasonography

基　　金：天津市卫计委科技基金项目（2013KZ086）

摘　　要：目的探讨剪切波弹性成像对不同时期深静脉血栓的诊断价值。方法建立兔深静脉血栓动物模型，应用无创的剪切波弹性成像技术分别测量1、4、7、10、14d的血栓杨氏模量值。结果血栓的弹性模量值随时间的延长而增长，从第1d的（4．00±1．42）kPa增长到第14d的（25．71±6．09）kPa，不同时间点的杨氏模量比较差异具有统计学意义（P〈0．05）。结论剪切波弹性成像能有效地反映不同时期血栓的弹性硬度，可以根据血栓的弹性硬度初步判断血栓的时期。Objective To evaluate the diagnostic value of shear wave elastography on deep venous thrombosis in different stage. Methods Models of rabbitsrdeep venous thrombosis have been established to noninvasively measure Youngts moduli of thrombosis in day 1,4,7,10 and 14 respectively by shear wave elastography. Results The elastic modulus of thrombosis increased with increment of the stages of thrombosis. Specifically, the mean Young＇s moduli of thrombosis increased from （4.0 ± 1.42）kPa （day 1 ） to （25.71±6.09）kPa （day 14）, with statistical differences between each two observation time points（ P〈 0.05）. Conclusions Shear wave elastography can effectively reflect the elasticity of thrombosis in different stages, and the stage of thrombosis can be estimated judging by quantitative ultrasound elasticity preliminarily.

关 键 词：弹性成像技术 静脉血栓形成 

分 类 号：R445.1[医药卫生—影像医学与核医学]