基于冠状动脉CTA图像对冠状动脉空间扭曲程度的量化测量  

Measurement of coronary tortuosity in three-dimension based on computed tomography coronary imaging

作　　者：刘一萱[1] 杨成明[1] 吴晨飞[2] 陈金华[3] 张伟国[3] 曾春雨[1] 王凌西[4] 

机构地区：[1]第三军医大学大坪医院野战外科研究所心血管内科,重庆400042 [2]重庆邮电大学计算机科学与技术系,重庆400065 [3]第三军医大学大坪医院野战外科研究所影像诊断科,重庆400042 [4]重庆大学土木工程学院,重庆400045

出　　处：《重庆医学》2015年第22期3093-3095,3098,共4页Chongqing medicine

摘　　要：目的提出对冠状动脉的扭曲程度进行准确的测量评价的新方法,为明确冠状动脉扭曲的所造成的影响提供有利条件。方法连续录入72例临床拟诊冠心病且均接受256排冠状动脉电子计算机断层扫描血管造影(CTA)检查患者的图像,经后处理后,提取心外膜下3支主要冠状动脉血管中轴,获取其在3维空间中的坐标,并对扭曲系数进行量化测量。结果心外膜下3支主要冠状动脉的三维空间扭曲系数分别为:左前降支6.66±7.54,左回旋支13.43±12.85,右冠状动脉17.61±7.67。通过对冠状动脉扭曲的建模检验证明该方法对扭曲评价的效果良好。结论此方法能对冠状动脉在三维空间的扭曲程度进行准确的定量化分析,且结果不受造影投射面、人为测量误差及血管长度的影响。Objective To quantitate coronary tortuosity and provide favorable conditions for understanding the hemodynamic effects caused by coronary tortuoslty. Methods We obtained all images from 72 patients who received coronary computed tomo- graphy scanning. After image post-processing, we extracted the medial axis of three main coronary vessel and analysed its coordinates on three dimensions. Then we calculated the tortuosity coefficient of coronary artery. Results Tortuosity coefficient was 6.66 ±7.54 in anterior descending, 13.43±12.85 in left circumflex, and 17.61 ±7.67 in right coronary artery. We had proved its validity by the changes in morphology with simulated shapes. Conclusion We proposed a new method for quantitating coronary tor- tuosity,by computed tomography coronary imaging. The measurement results would not be affected by projection plane, vessel length or other artificial factors.

关 键 词：冠状血管 体层摄影术 螺旋计算机 冠状动脉扭曲 CT冠状动脉成像 扭曲系数 

分 类 号：R543.3[医药卫生—心血管疾病]