增强T2 FLAIR在病毒性脑炎诊断中的应用  

Application of contrast-enhanced T2 fluid-attenuated inversion recovery in diagnosis of viral encephalitis

作　　者：牛敬莲[1] 刘新彦[2] 耿左军[3] 

机构地区：[1]河北省石家庄市第五医院放射科,050021 [2]河北北方学院附属第二医院 [3]河北医科大学第二医院放射科

出　　处：《河北医药》2015年第15期2245-2249,共5页Hebei Medical Journal

摘　　要：目的分析增强后T2液体衰减反转恢复(FLAIR)序列与增强T1WI在病毒性脑炎诊断中的显示病灶的差异,为临床提供有价值的影像资料。方法 36例病毒性脑炎患者均行头颅常规T1WI、T2WI、FLAIR序列及增强检查。由两位资深影像科医师盲法比较3个序列(平扫FLAIR、增强FLAIR、增强T1WI)显示病灶的能力。结果平扫FLAIR序列共检出病变22例,占61.1%(22/36);增强T1WI序列检出强化病变14例,占38.9%(14/36);增强FLAIR序列检出强化病变20例,占55.6%(20/36)。增强FLAIR序列比增强T1WI检出脑实质或脑膜病变例数多,差异有统计学意义(P<0.05);且增强FLAIR序列显示脑实质病灶较增强T1WI范围稍广、边缘显示更清晰,但增强T1WI强化程度略高于增强FLAIR序列;二者对脑实质内病变的显示比较分析,差异无统计学意义(P>0.05)。结论增强FLAIR序列应被视为增强T1WI的补充序列,在病毒性脑炎的诊断中可列为一项常规检查。Objective To analyze the difference between T2 fluid-attenuated inversion recovery （FLAIR） and T1WI after contrast enhancement in displaying the focus of viral encephalitis in order to provide more valuable image data in clinic. Methods Thirty-six patients with viral encephalitis were examined by routine cranial T1WI, T2WI, FLAIR sequences and contrast enhancement, respectively, the examination results especially for the ability of displaying lesions of disease were observed and compared by two senior radiologists by means of double blind method among three sequences including plain scan FLAIR, contrast-enhanced T1WI, contrast-enhanced FLAIR. Results Twenty-two cases （22/36） of cranial lesions were detected by plain scan FLAIR, which accounted for 61. 1%;14 cases （14/36） of cranial lesions were detected by contrast-enhanced T1 WI,which accounted for 38.9% ;20 cases （20/36） of cranial lesions were detected by contrast-enhanced FLAIR, which accounted for 55.6%. The detected lesions of in cerebral parenchyma or meninges by contrast-enhanced FLAIR were significantly more than those by contrast-enhanced T1WI （ P 〈 0.05 ）, moreover, the range of the lesions in cerebral parenchyma was showed wider and clearer by contrast-enhanced FLAIR, as compared with that by contrast-enhanced T1WI, however, the enhancement degree of contrast-enhanced T1WI was more than that of contrast-enhanced FLAIR, there was no significant difference in the ability of displaying lesions in cerebral parenchyma between contrast-enhanced T1WI and contrast-enhanced FLAIR （ P 〉 0.05 ）. Conclusion The contrast-enhanced FLAIR should be regarded as a supplement sequence of contrast-enhanced T1WI, which should be used as a routine examination in diagnosis of viral encephalitis.

关 键 词：液体衰减反转恢复序列 病毒性脑炎 增强扫描 T1WI 

分 类 号：R373.31[医药卫生—病原生物学]