心脑宁片治疗冠心病心绞痛的临床研究  

Clinical Study of Xinnaoning Tablet in Treatment of Angina Pectoris of Coronary Heart Disease

作　　者：苏峰[1] 谢国旗[1] 朱改针[1] 张三林[1] 张正臣[1] 赵俭昌 

机构地区：[1]中国人民解放军第371中心医院,河南新乡453000

出　　处：《中医学报》2015年第7期1041-1043,共3页Acta Chinese Medicine

基　　金：河南省科学技术厅2009年科技发展计划(092102310202)

摘　　要：目的:观察心脑宁片治疗冠心病心绞痛的临床疗效。方法:将300例冠心病心绞痛患者随机分为治疗组和对照组,每组各150例。对照组常规服用肠溶阿司匹林、硝酸酯类、β-受体阻滞剂及钙离子拮抗剂等西药常规治疗;治疗组在对照组基础上加用心脑宁片,每次4片,每日3次。两组患者均以10 d为1个疗程,连用2个疗程。两组患者均在治疗期间心绞痛发作时临时含服硝酸甘油,高血压病、糖尿病分别给予降血压、降血糖等治疗。结果:治疗组有效率为97%,对照组有效率为83%,两组临床疗效比较,差异有统计学意义(P<0.05)。治疗组对于缓解心绞痛症状、改善心电图、调节血流变均有显著疗效,优于对照组(P<0.05)。结论:心脑宁片治疗冠心病心绞痛疗效显著。Objective：To explore the clinical curative effect of Xinnaoning tablet in treatment of angina pectoris of coronary heart dis-ease.Methods：300 cases of angina pectoris patients were randomly divided into treatment group and control group,1 50 cases in each group.The control group was given conventional enteric coated aspirin,nitrates,beta blockers,and calcium ion antagonist agent as con-ventional western medicine treatment and treatment group was given Xinnaoning tablets,4 tablets each time,3 times a day.Two groups were treated with 1 0 d as 1 course,treatment for 2 courses.During the treatment,the two groups of angina pectoris attack can be given temporarily sublingual nitroglycerin,hypertension,diabetes to lower blood pressure,lower blood sugar and other treatment.Results：The effective rate was 97% in treatment group and 83% in the control group.Compared the clinical efficacy of two groups,the difference was statistically significant（P 〈0.05）.The treatment group to alleviate the symptoms of angina pectoris,ECG,blood flow change has a reliable effect,better than that of control group.Conclusion：Xinnaoning tablet in the treatment of coronary heart disease angina pectoris has curative effect.

关 键 词：冠心病心绞痛 心脑宁片 肠溶阿司匹林 

分 类 号：R259.414[医药卫生—中西医结合]