罗哌卡因和玻璃酸钠在膝关节镜术后镇痛的临床应用  

Clinical application of sodium hyaluronate and ropivacaine in analgesic efficacy of knee arthroscopy

作　　者：胡伟全[1] 王瑞[1] 赵建宁[1] 

机构地区：[1]南京大学医学院临床学院(南京军区南京总医院)骨科,南京210093

出　　处：《临床与病理杂志》2015年第7期1339-1343,共5页Journal of Clinical and Pathological Research

基　　金：江苏省临床医学科技专项资助(BL2012002);南京市科研课题(201402007)~~

摘　　要：目的:探讨罗哌卡因和玻璃酸钠在膝关节镜治疗半月板损伤术后镇痛的临床效果。方法:将2014年10月至2015年4月在南京军区南京总院骨科关节外科收治的40例半月板损伤患者随机分为2组,每组20人,A组:关节腔内注射罗哌卡因和玻璃酸钠;B组:静脉镇泵给药镇痛和关节腔内注射玻璃酸钠。比较两组疼痛视觉模拟评分(visual analogue scale,VAS)、满意度、辅助口服镇痛药物塞来昔布使用量及不良事件发生率、住院时间。结果:手术后24 h内,在VAS评分、病人满意度、辅助口服止痛药物使用量、不良事件发生率及出院时间方面,A组具有明显优势(P<0.05)。结论:罗哌卡因和玻璃酸钠关节腔内注射可以作为膝关节镜术后镇痛的新选择。Objective： To investigate the clinical effect of ropivacaine and sodium hyaluronate in postoperative analgesia treatment after the knee arthroscopy for the meniscus injury. Methods： A total of 40 patients with meniscus injury from October 2014 to April 2015 in Nanjing General Hospital of Nanjing Military Command were divided into two groups randomly, 20 patients in each group, group A was given intraarticular injection of ropivacaine and sodium hyaluronate and group B was treated with intravenous analgesia and intraarticular injection of sodium hyaluronate. Compared of two groups with visual analog scale （VAS）, degree of satisfaction, usage amount of celecoxib, adverse event rates and hospital stays. Results： Within 24 hours after operation, the VAS score, patient satisfaction, consumption of analgesics, adverse effects and hospital stays were better in A group （P〈0.05）. Conclusion： Intraarticular injection of ropivacaine and sodium hyaluronate can therefore be proposed as an option for patients underwent knee arthroscopy.

关 键 词：罗哌卡因 玻璃酸钠 半月板损伤 关节镜手术 

分 类 号：R687.4[医药卫生—骨科学]