阿片类药物在硬膜外腔镇痛中的效果观察  

Observation of Opioids in Epidural Analgesia

作　　者：杨少杰 

机构地区：[1]甘肃省第二人民医院麻醉科,甘肃兰州730000

出　　处：《中国医药指南》2015年第23期29-30,共2页Guide of China Medicine

摘　　要：目的 阿片类药物在硬膜外腔镇痛效果的临床应用观察。方法 选择646例12~84岁的患者,随机均分为吗啡-氟派啶组、度冷丁-氟派啶组、罂粟碱-氟派啶组和度冷丁-罂粟碱-氟派啶组。观察四组的镇痛时间、恶心呕吐、尿潴留的例数以及对肠蠕动、呼吸功能的影响。结果 吗啡-氟派定组镇痛时间较其他三组明显长;恶心呕吐、尿潴留较其他三组发生率高,但四组对患者的肠蠕动、呼吸功能抑制无明显影响。结论 阿片类药物在硬膜外腔镇痛用于术后患者效果确切,对恶心呕吐、尿潴留影响小,对肠蠕动、呼吸功能无明显影响,值得推广。Objective To observe the clinical application of opioids in epidural analgesia. Methods 646 patients aged 12-84 years, were randomly divided into morphine and pethidine group, fluorine piperidine-fluorine piperidine group, narceine fluorine piperidine group and dolantin-papaverine-fluorine piperidine group. The number of cases in four groups were observed the analgesia time, nausea and vomiting, urinary retentionand the effect onrespiratory function of intestinal peristalsis. Results Morphine analgesia group of fluorine appointed time was significantly longer than the other three; nausea and vomiting, urinary retention was higher than that of the other three groups with high incidence rate, but the four groups of patients with intestinal peristalsis, respiratory function inhibition had no significant effect. Conclusion Opioids in epidural analgesia for postoperative patients with definite effecton nausea and vomiting, urinary retention, little effect on intestinal peristalsis, respiratory function, no significant effect, worthy of promotion.

关 键 词：阿片类药物 硬膜外腔镇痛 效果观察 

分 类 号：R614[医药卫生—麻醉学]