2014年甘肃口岸朝觐归国人员呼吸道病毒监测分析  

Surveillance analysis of respiratory viruses of entry pilgrims in Gansu port during 2014

作　　者：刘芳 高晓强 卢明珠 焦志刚 罗永 尹海萍 赵庆华 杨娅翎 王宇平[2] 王军平 

机构地区：[1]甘肃国际旅行卫生保健中心,甘肃兰州730020 [2]福建国际旅行卫生保健中心

出　　处：《中国国境卫生检疫杂志》2015年第3期186-189,共4页Chinese Journal of Frontier Health and Quarantine

基　　金：国家质检总局科技计划项目(2014IK068)

摘　　要：目的了解2014年甘肃口岸朝觐归国人员呼吸道病毒感染情况,重点监测中东呼吸综合征(MERS)及流感等呼吸道传染病病原流行情况。方法采集甘肃口岸朝觐人员入境检疫查验中发现流感样病例咽拭子样本84份,通过世界卫生组织(WHO)推荐的荧光定量RT-PCR方法检测中东呼吸综合征相关病毒,同时针对病毒RNA样本开展甲、乙型流感病毒、甲型H1N1流感病毒、甲型H3流感病毒、甲型H5N1流感病毒、甲型H7N9流感病毒、冠状病毒NL63型、HKU1型、229E型、OC43型、人博卡病毒、人偏肺病毒、呼吸道合胞病毒进行检测。结果所有样本均未检出中东呼吸综合征病毒,有9份样本检出其他12种病原核酸的其中1种,分别为甲型H3N2流感病毒(5例)、冠状病毒(3例)、偏肺病毒(1例),病毒总检出率为10.7%,其中甲型流感病毒检出率最高,为5.9%。呼吸道传染病病毒阳性病例以老年人(≥60岁)为主,在性别分布上无差异。结论 2014年甘肃口岸归国朝觐人员未检出MERS病毒感染,具有流感样病例的朝觐归国人员主要以甲型流感病毒为呼吸道传染病病原,并以老年人为主,初步掌握甘肃口岸朝觐归国人员病毒性呼吸道传染病病原谱组成,为开展朝觐人员健康保障工作提供参考。Objective To understand the status of respiratory virus infection of entry pilgrims in Gansu port during2014, especially on the epidemiological factors of MERS,influenza and other respiratory infectious disease virus.Methods A total of 84 throat swab specimens were collected from influenza-like illness cases detected by health inspection and quarantine in Gansu port. RT-PCR method recommended by WHO were used to detect MERS virus 、the influenza virus A,B, H1N1,H3N2,H5N1,H7N9,coronavirus NL63、coronavirus HKU1、coronavirus 229E、coronavirus OC43, Bocavirus,metapneumovirus and respiratory syncytial virus. Results No MERS virus was detected in collected samples. The other respiratory infectious disease viruses were detected in 9 sample（5 cases of influenza virus H3N2, 3 cases of coronavirus, 1 case of metapneumovirus）. The total disease detection rate was 10.7%.Influenza virus A（H3N2） was the most frequent respiratory virus（5.9%,5/84）. Respiratory virus infection was mainly found in old ones whose age was more than 60,while no statistic difference was found for sex. Conclusion The MERS virus had not been detected in entry pilgrims at Gansu port during this year. The influenza virus A was likely the most frequent pathogen of respiratory virus infection during pilgrimage. The respiratory viral spectrum of entry pilgrims in Gansu port was revealed tentatively, which can provide basis for the protection of pilgrims＇ health.

关 键 词：中东呼吸综合征 朝觐人员 呼吸道感染 监测 病毒感染 流感 

分 类 号：R183.3[医药卫生—流行病学]