加味生脉散抗小鼠运动性疲劳的实验研究  

An experimental study of Jiawei Shengmai powder for treating exercise-induced fatigue in mice

作　　者：聂琦[1] 叶菁[2] 靳松[3] 

机构地区：[1]江西中医药大学,江西南昌330004 [2]江西中医药大学附属医院,江西南昌330006 [3]浙江省温州市中医院,浙江温州325000

出　　处：《湖南中医杂志》2015年第7期159-161,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：江西省卫生和计划生育委员会中医药科研计划资助项目(编号:2013A208)

摘　　要：目的:观察加味生脉散对小鼠抗运动性疲劳能力的影响。方法:挑选能游泳的昆明种实验小鼠40只,将其分为对照组及加味生脉散低、中、高剂量组,各组每天游泳1h后灌服相应药物,连续15d,观察比较各组末日体质量、力竭性游泳时间及力竭后血乳酸含量。结果:加味生脉散各剂量组小鼠末日体质量与对照组比较,差异无统计学意义(P>0.05);加味生脉散中、高剂量组负重游泳时间较对照组延长(P<0.05),血乳酸含量较对照组降低(P<0.05)。结论:加味生脉散具有抗小鼠运动性疲劳的作用。Objective：To observe the impacts of Jiawei Shengmai powder（JSP）on the resistance against exercise induced fatigue in mice. Methods：Forty Kunming mice that were able to swim were selected and divided into controlgroup,low- dose JSP group, medium- dose JSP group, and high -dose JSP group. Mice in each group were given specific drugs after one - hour swimming every day. Body mass, exhaustive swimming time, and blood lactate con- centration after exhausting exercise were determined and compared between groups after 15 continuous days of treat- ment. Results：There was no significant difference in body mass on the last day between the control group and the JSP - treated groups （ P 〉 0. 05 ）. The medium - dose and high - dose JSP groups had significantly prolonged ex- haustive swimming time and significantly lower blood lactate concentrations than the control group （ P 〈 0. 05 ; P 〈 0. 05 ）. Conclusion ： JSP can protect against exercise - induced fatigue in mice.

关 键 词：运动性疲劳 生脉散 小鼠 血乳酸 实验研究 

分 类 号：R285.5[医药卫生—中药学]