不同采收期何首乌中多元功效物质的动态积累分析  

Dynamic accumulation analysis on bioactive constituents of Polygonum multiflorum in different collection periods

作　　者：罗益远 刘娟秀[1] 刘训红[1] 兰才武 侯娅[1] 马阳[1] 王胜男[1] 蔡宝昌[1] 

机构地区：[1]南京中医药大学,江苏南京210023 [2]贵州昌昊中药发展有限公司,贵州凯里556000

出　　处：《中国中药杂志》2015年第13期2565-2570,共6页China Journal of Chinese Materia Medica

基　　金：国家科技支撑计划项目(2011BAI13B04);江苏高校优势学科建设工程项目(ysxk-2014);江苏省中药炮制重点实验室开放式课题(zypz007)

摘　　要：考察不同采收期何首乌中多元功效物质的动态变化规律,探讨何首乌药材的适宜采收期。采用胶束电动毛细管色谱二极管阵列检测法(MEKC-DAD)测定不同采收期何首乌中二苯乙烯苷、蒽醌类及儿茶素的含量,用主成分分析法对多元功效物质进行综合评价。不同采收期何首乌中多元功效物质的含量呈现动态变化,二苯乙烯苷的含量11月份最高;结合蒽醌的总量11—12月份最高;儿茶素的含量在9月份相对较高;主成分分析综合评价显示,11月份采收的何首乌药材综合评价指数明显高于其他采收期样品。11月份为何首乌药材适宜的采收期,与当地传统采收期基本一致。To study the dynamic change law of bioactive constituents from Polygonum multiflorum, and to explore the optimal har- vest period of P. multiflorum. Determination of stilbene glucoside, anthraquinones and catechin from P. multiflorum in different har- vest times by MEKC-DAD, and principal component analysis （PCA） was used to comprehensive evaluation for bioactive constituents. There are obvious differences among the contents of active ingredients in various collecting periods samples, the content of stilbene glu- coside was the highest in November, the total content of combined anthraquinone was the highest in November and December, the con- tent of catechin was the highest in September. The comprehensive evaluation index obtained with principal component analysis showed that the sample collected in November is significantly higher than those with other samples. The optimal harvest period of P. multiflo-rum is November.

关 键 词：何首乌 胶束电动毛细管色谱二极管阵列检测法 多元功效物质 动态积累 

分 类 号：R282.4[医药卫生—中药学]