Relief Effect of Bevacizumab on Severe Edema Induced by Re-irradiation in Brain Tumor Patients  

作　　者：Ge Shen Ying-Jie Wang Yan-Jun Guan Da-Peng Dong Gang Yang Dan Li Rui-Min Hao Hui-Ru Sun Ming Zhou Kun-Peng Wang Shi-Xiang Zhou Qin-Wen Wang Shi-Kai Wu Yan-Jun Zeng 

机构地区：[1]Department of Radiation Oncology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China [2]Department of Radiation Oncology, Army Radiation Cancer Center, Air Force General Hospital, Beijing 100036, China [3]Department of Medicine, General Hospital of Chinese Armed Police, Beijing 100039, China [4]Department of Bioengineering, Biomedical Engineering Center, Beijing University of Technology, Beijing 100022, China

出　　处：《Chinese Medical Journal》2015年第15期2126-2129,共4页中华医学杂志（英文版）

摘　　要：INTRODUCTION Brain edema is a serious clinical event and could cause various neurological symptoms such as dizziness and headache.Drugs frequently used to relieve brain edema include steroid,dehydrant （e.g.,mannitol）,and diuretics.But the effects of these drugs were limited in patients with severe edema.Bevacizumab has been applied in the treatment of cerebral radiation necrosis. Case studies have reported on the application of bevacizumab in the treatment of severe brain edema. In the present study,we describe significant effects of bevacizumab on severe brain edema in patients with re-irradiation.INTRODUCTION Brain edema is a serious clinical event and could cause various neurological symptoms such as dizziness and headache.Drugs frequently used to relieve brain edema include steroid,dehydrant （e.g.,mannitol）,and diuretics.But the effects of these drugs were limited in patients with severe edema.Bevacizumab has been applied in the treatment of cerebral radiation necrosis. Case studies have reported on the application of bevacizumab in the treatment of severe brain edema. In the present study,we describe significant effects of bevacizumab on severe brain edema in patients with re-irradiation.

关 键 词：BEVACIZUMAB Brain Tumor RE-IRRADIATION Severe Edema 

分 类 号：S858.315.3[农业科学—临床兽医学] TP317.4[农业科学—兽医学]