儿童外阴阴道炎380例病原学与耐药性分析  

Analysis of Pathogens and Drug Resistance in 380 Children with Vulvovaginitis

作　　者：卢文敏[1] 胡霄颖[1] 叶莹[1] 王榴慧[1] 

机构地区：[1]复旦大学附属儿科医院皮肤科,上海201102

出　　处：《中国药房》2015年第23期3216-3219,共4页China Pharmacy

摘　　要：目的:探讨儿童外阴阴道炎的菌种分布特征,分析其耐药特点,为指导临床合理用药提供依据。方法 :收集整理2014年我院皮肤科门诊380例儿童外阴阴道炎患儿阴道分泌物常规细菌及真菌培养阳性结果共409株。记录其培养结果及药敏结果。结果:菌群分布前5位者由高至低依次为大肠埃希菌[36.67%(150/409)]、流感嗜血杆菌[20.29%(83/409)]、A组溶血性链球菌[13.20%(54/409)]、肺炎克雷伯菌[8.80%(36/409)]、金黄色葡萄球菌[5.37%(22/409)]。结论:儿童外阴阴道炎的主要致病菌为革兰阴性杆菌,因而在临床使用抗菌药物时应特别注意耐药现象以提高药物疗效。治疗中应以药敏试验结果为依据,合理使用抗菌药物。OBJECTIVE：To explore the characteristics of pathogens distribution of pediatric vulvovaginitis and drug resistance,and to provide reference for clinical drug use. METHODS：409 strains of positive routine bacteria and fungus culture were collected from 380 children with vulvovaginitis in 2014. The pathogens culture and drug sensitivity were recorded. RESULTS：The top 5 bacteria were Escherichia coli [36.67%（150/409）],Haemophilus influenzae [20.29%（83/409）],Streptococcus hemolyticus group A [13.20%（54/409）],Klebsiella pneumonia [8.80%（36/409）] and Staphylococcus aureus [5.37%（22/409）]. CONCLUSIONS：The main pathogenic bacteria of pediatric vulvovaginitis is Gram negative bacilli,so that drug resistance should be paid attention to improve therapeutic efficacy when antibiotics are used in the clinic. The result of sensitivity test should be taken as basis for rational application of antibiotics in the treatment.

关 键 词：儿童 阴道炎 病原菌 药敏试验 耐药率 

分 类 号：R969.1[医药卫生—药理学] R978.1[医药卫生—药学]