2012-2013年铜绿假单胞菌下呼吸道感染的耐药性分析  

Drug Resistance of Lower Respiratory Infection Caused by Pseudomonas Aeruginosa During 2012-2013

作　　者：潘杨[1] 李建英[1] 刘远程[1] 钱效森[1] 

机构地区：[1]北京民航总医院呼吸内科,北京100123

出　　处：《黑龙江医药》2015年第4期739-742,共4页Heilongjiang Medicine journal

摘　　要：目的:了解本院呼吸内科2012-2013年铜绿假单胞菌下呼吸道感染的耐药性,为临床治疗铜绿假单胞菌感染提供依据。方法:对医院呼吸内科2012年1月-2013年12月收治的59例铜绿假单胞菌下呼吸道感染住院患者进行统计,分析其细菌学特征及耐药情况。结果:2年分离59例铜绿假单胞菌对多粘菌素、哌拉西林/他唑巴坦、头孢他啶、阿米卡星的耐药率最低,分别为11.9%、25.4%、27.1%、28.8%,其次为美洛培南、头孢吡肟、、环丙沙星、左氧氟沙星、亚胺培南,耐药率分别为35.6%、35.6%、37.3%、39.0%、42.4%,对其他抗菌药物耐药率较高。结论:铜绿假单胞菌对多种抗生素产生不同程度的耐药,治疗时应加强药敏试验,及时合理选用敏感的抗菌药物。Objective： To investigate the drug resistance of lower respiratory infection caused by Pseudomonas aeruginosa during 2012-2013 in Department of Respiratory Medicine at Beijing General Hospital of Civil Aviation, in order to guide the clinical treat- ment. Methods： A total of 59 lower respiratory infection caused by Pseudomonas aeruginosa were collected from January 2012 to De- cember 2013, and then statistically analyzed. The bacteriological characteristics and drug resistance were also analyzed. Results： Dur- ing the 2 years, the drug resistance rates of the Pseudomonas aeruginosa to polymyxin, tazobacta-piperacillin, ceftazidime and amika- chi were 11.9%, 25.4%, 27.1% and 28.8%, respectively. The drug resistance rates to meropenem, cefepime, ciprofloxacin, levoflocacin and imipenem were 35.6%, 35.6%, 37.3%, 39.0% and 42.4%, respectively. The drug resistance rates to other antibiotics were relatively high. Conclusion： Pseudomonas aeruginosa presents a different degree of resistance against multiple antibiotics. The susceptibility test is required to be strengthened in order to effectively choose susceptible antibiotics.

关 键 词：铜绿假单胞菌 耐药性 药敏试验 

分 类 号：R56[医药卫生—呼吸系统]