不同性别老年急性心肌梗死患者血脂特点及其与冠状动脉病变的关系  

Characteristics of lipids in elderly patients of different genders with acute myocardial infarction and its relationship with coronary artery lesions

作　　者：李昭[1] 李南[1] 张京梅[1] 李志忠[1] 王苏[1] 黄觊[1] 王茜[1] 张冬花[1] 吴翔宇[1] 孙涛[1] 阴赪茜[1] 程宇彤[1] 

机构地区：[1]首都医科大学附属北京安贞医院心内科,北京100029

出　　处：《中华实用诊断与治疗杂志》2015年第8期745-748,共4页Journal of Chinese Practical Diagnosis and Therapy

基　　金：国家自然科学基金资助项目(81000130);首都临床特色应用研究(Z131107002213042)

摘　　要：目的探讨不同性别老年急性心肌梗死患者的血脂特点，分析其与冠状动脉病变程度的关系。方法行冠状动脉造影术急性心肌梗死老年患者336例，男性组173例，女性组163例，将男性组和女性组依据年龄分为60-70岁和〉70-79岁2个亚组，依据冠状动脉造影结果分为单支病变组及多支病变2个亚组，比较不同性别、不同年龄及不同病变程度患者血清总胆固醇（totalcholesterol，TC）、低密度脂蛋白胆固醇（10wdensitylipoprotein-cholesterol，LDL—C）、三酰甘油（triacylglycerol，TG）及高密度脂蛋白胆固醇（highdensitylipoprotein—cholesterol，HDL—C）水平。结果女性组年龄60-70岁48例（单支病变14例，多支病变34例），〉70-79岁115例（单支病变36例，多支病变79例）；男性组年龄60-70岁70例（单支病变12例，多支病变58例），〉70-79岁103例（单支病变10例，多支病变93例），女性组TC[（4．76±111）mmol／L]、TO[（1．75±0．91）mmol／L]及LDL-CF（3．25±0．91）mmol／L]水平高于男性组[（4．41±0．98）、（1．51±0．76）、（2．80±0．82）mmol／L]（P〈0．05）；女性〉70-79岁组TCE（4．77±1．14）mmol／L]、TGF（1．67±0．90）mmol／L]及LDL-C[（3．23±0．96）mmol／L]高于男性〉70-79岁组[（4．26±0．90）、（1．36±0．56）、（2．66±0．76）mmol／L]（P〈0．05）；女性单支病变组TG[（1．93±0．84）mmol／L]水平高于男性单支病变组[（1．33±0．57）mmol／L]（P〈0．05），多支病变组TC[（4．82±1．06）mmol／L]、LDL—C[（3．30±0．86）mmol／L]水平高于男性多支病变组[（4．39±0．98）、（2．78±0．83）mmol／L]（P〈0．05）；女性年龄〉70-79岁并单支病变组TGF（1．96±0．95）mmol／L]水平高于男性〉70-79岁并单支病变组[（o．85±0．11）mmol／L]（P〈0．05）；女性年龄〉70-79岁并多支病变组TC[（4．83±1．04）mmol／L]及LDL—cE（3．29±0．86�Objective To investigate the characteristics of lipids in elderly patients of different genders with acute myocardial infarction （AMI） and its relationship with coronary artery lesions. Methods A total of 336 elderly AMI patients undergoing coronary angiography included 173 males and 163 females, who were respectively divided into female and male 60- to 70-year-old groups and ∽70- to 79-year-old groups. Also these patients were divided into single-vessel- lesion group and multiple-vessel-lesion group according to the angiographic results. The levels of total cholesterol （TC）, low density lipoprotein-eholesterol （LDL-C）, triaeylglycerol （TG） and high density lipoprotein-cholesterol （HDL-C） were detected and compared between patients with different sex, age and lesion degree. Results In 60- to 70-year-old female group （n = 48）, there were 14 patients with single-vessel lesions and 34 patients with multiple-vessel lesions.In 〉70- to 79-year- old female group （n= 115）, there were 36 patients with single-vessel lesions and 79 with multiple- vessel lesions. In 60- to 70-year-old male group （n=70）, there were 12 patients with single-vessel lesions and 58 patients with multiple-vessel lesions. In 〉70- to 79-year-old male group （n= 103）, there were 10 patients with single-vessel lesions and 93 with multiple-vessel lesions. The levels of TC （（4.76∽1.11） mmol/L）, TG （（1.75∽0.91） mmol/L） and LDL-C （ （3.25 ±0.91） mmol/L） were higher in female patients than those in male patients （ （ 4.41 ± 0.98）, （ 1. 51±0.76）, （2. 80±0.82） mmol/L） （P〈0.05）. The levels of TC （（4.77±1.14） mmol/L）, TG （（1.67±0.90） mmol/L） and LDL-C （（3.23±0.96） mmol/L） were higher in 〉70- to 79-year-old female group than those in 〉70- to 79-year-old male group （（4.26±0.90）, （1.36±0. 56）, （2.66±0.76） mmol/L） （P〈0.05）. The level of TG was higher in female patients with single-vessel lesions （（1.93±0.84） mmo

关 键 词：急性心肌梗死 老年 血脂 单支病变 多支病变 

分 类 号：R542.22[医药卫生—心血管疾病]