机构地区:[1]郑州大学人民医院 [2]河南省人民医院超声科,郑州450003 [3]河南省人民医院心内科,郑州450003 [4]香港中文大学威尔斯亲王医院心内科,香港999077
出 处:《中华实用诊断与治疗杂志》2015年第8期776-778,781,共4页Journal of Chinese Practical Diagnosis and Therapy
基 金:国家卫生计生委2013-2014年度国家临床重点专科建设项目
摘 要:目的探讨实时三平面组织同步显像(tissue synchronization imaging,TSI)技术用于监测心脏再同步化治疗(cardiac resynchronization theraphy,CRT)前、后患者左心室收缩同步性改变的价值。方法心力衰竭患者30例,均行CRT治疗,分别于CRT治疗前和治疗后3个月行超声心动图检查,测量左心室舒张末期内径(left ventricular enddiastolic dimension,LVEDD)、左心室收缩末期内径(left ventricular end-systolic dimension,LVESD)及左室射血分数(left ventricular ejection fraction,LVEF),并应用TSI技术测量左心室壁基底段和中间段12个心肌节段的局部收缩达峰时间(time to peak systolic velocities,Tp),12个心肌节段收缩达峰时间最大差(the maximal difference of Tp among 12segments,12-Tp-DIF)和标准差(the standard deviation of Tp among 12segments,12-Tp-SD);采用Pearson相关分析12-Tp-DIF和12-Tp-SD与LVEF的相关性。结果治疗3个月后LVEDD[(67.2±2.5)mm]、LVESD[(53.5±5.5)mm]、12-Tp-DIF[(138.9±40.1)ms]、12-Tp-SD[(44.6±10.9)ms]均较治疗前[LVEDD(72.2±2.0)mm、LVESD(61.9±5.0)mm、12-Tp-DIF(205.0±27.9)ms、12-Tp-SD(69.9±11.7)ms]明显降低(P<0.05),LVEF[(39.4±9.6)%]较治疗前[(26.8±4.9)%]明显增高(P<0.05);Pearson相关分析结果显示,12-Tp-DIF和12-Tp-SD与LVEF具有良好相关性(r=-0.720,P=0.000;r=-0.740,P=0.000)。结论实时三平面TSI技术可定量评价行CRT治疗前、后患者左心室心肌收缩同步性的改变。Objective To investigate the value of real-time thriplane tissue synchronization imaging (TSI) to monitoring the changes of left ventricular systolic synchrony before and after cardiac resynchronization therapy (CRT). Methods Thirty patients with heart failure being scheduled for CRT received echocardiography to measure the left ventricular end- diastolic dimension (LVEDD) and left ventricular end-systolic dimension (LVESD) and left ventricular ejection fraction (LVEF) before and 3 months after CRT. The TSI technique was used to detect the time to peak systolic velocities (Tp) of left ventricle basal and middle segments (12 segments), the maximal difierence of Tp among 12 segments (12-Tp-DIF) and standard deviation of Tp among 12 segments (12-Tp-SD). Pearson relevant analysis was used to analyze the correlations of 12 Tp-DIF and 12-Tp-SD with LVEF. Results After 3-month treatment, LVEDD ((67.2±2.5) mm), LVESD ((53.5±5.5) mm), 12-Tp-DIF ((138.9±40.1) ms) and 12-Tp-SD ((44.6±10.9) ms) were lower than those before treatment ((72.2±2.0) mm, (61.9±5.0) mm, (205.0±27.9) ms, (69.9±11.7) ms), and LVEF was higher after 3-month treatment ((39.4±9.6)%) than that before treatment ((26.8±4.9)%) (P〈0.05). Pearson relevant analysis revealed 12-Tp-DIF and 12-Tp-SD were correlated with LVEF (r=- 0. 720, P= 0. 000; r=- 0. 740, P= 0. 000). Conclusion Real-time thriplane TSI can quantitatively evaluate the changes of left ventricular systolic synchronicity before and after CRT.
关 键 词:心力衰竭 心脏再同步化治疗 超声心动图 实时三平面 组织同步显像
分 类 号:R541.6[医药卫生—心血管疾病] R540.45[医药卫生—内科学]
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