北京地区1287例婴幼儿腹泻A组人类轮状病毒流行特征分析  

Epidemic Characteristics of Group A Rotavirus Infection in 1287 cases of Childhood Diarrhea in Beijing

作　　者：赵明英[1] 梁国威[1] 冯京全[1] 

机构地区：[1]航天中心医院检验科,北京100049

出　　处：《临床输血与检验》2015年第4期324-326,共3页Journal of Clinical Transfusion and Laboratory Medicine

摘　　要：目的调查北京地区婴幼儿腹泻A组人类轮状病毒流行特征。方法收集2013年5月～2014年4月本院儿科门诊腹泻患儿粪便共计1 287例（年龄范围1个月～11岁;男性757例,女性530例）。采用胶体金免疫层析法快速检测A组人类轮状病毒。结果在1 287例腹泻患儿标本中,A组轮状病毒阳性例数（阳性率）为338例（26.2%）,男、女性患儿阳性率的差异无统计学意义（25.8%vs 26.7%,P=0.437）。年龄分组显示,〈1岁、1岁、2岁、3～4岁和〉4岁患儿A组轮状病毒感染率分别为25.5%、28.3%、25.3%、21.4%和16.4%。高发季节为11月和12月（53.3%和44.4%）,低发季节为6～9月（〈10%）。结论北京地区约1/4的婴幼儿腹泻是由轮状病毒所致,〈2岁婴幼儿和秋冬季前应重点防护和监测。Objective To investigate the epidemic characteristics of group A rotavirus infection in children′s diarrhea in Beijing.Methods 1 287 stool specimens of children with diarrhea（aged from 1month-to 11yeas）from 757 boys and 530 girls were collected in outpatient pediatric clinic from May in 2013 to April.The antigen of rotavirus was measured by the gold immunochromatographic assay.Results Among 1 287 cases,338cases（26.2%）were positive for rotavirus antigen,and no significant difference of positive rate between boys and girls were observed（25.8% vs 26.7%,P=0.437）.The positive rates of rotavirus infection were 25.5%,28.3%,25.3%,21.4% and 16.4%,respectively in age of1,1,2,3～4and 4years The peak of the viral infection was November and December（53.3% and 44.4%）,and the low incidence was from June to September（10%）,respectively.Conclusion A quarter of childhood diarrheas were infected by group A rotavirus in Beijing area.The measures for preventing and monitoring rotavirus infection should be given to those with age of2years and in the seasons from autumn to winter.

关 键 词：儿童 腹泻 轮状病毒 流行病学 

分 类 号：R442.2[医药卫生—诊断学] R181.22[医药卫生—临床医学]