蒙古黄芪不同药用部位中黄芪甲苷的含量测定  

Determination of astragaloside Ⅳ in different medicinal parts of Astragalus membranaceus(Fisch.) Bge.var.mongholicus(Bge.) Hsiao

作　　者：杨庆珍[1] 刘德旺[2] 黄林芳[1] 蔡敏[2] 

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所,北京100193 [2]内蒙古医科大学,内蒙古呼和浩特010080

出　　处：《中国生化药物杂志》2015年第3期156-158,共3页Chinese Journal of Biochemical Pharmaceutics

基　　金：国家自然科学基金面上项目(81274013;81473315);国家自然科学基金重点项目(81130069);国家科技支撑计划(2011BAI07B01)

摘　　要：目的：测定并比较蒙古黄芪不同药用部位中黄芪甲苷的含量。方法采用高效液相色谱（ HPLC）法，测定蒙古黄芪药材主根、须根、根头和全根中黄芪甲苷含量。结果黄芪药材各药用部位黄芪甲苷含量高低顺序为：须根＞全根＞主根＞根头；内蒙古地区蒙古黄芪甲苷含量是2010年版《中国药典》规定黄芪甲苷含量标准的1．85～2．7倍。结论传统的加工方式中直接除去的须根，可作为提取黄芪甲苷的原材料。本研究可为蒙古黄芪的采收加工提供参考。Objective To determine and compare the contents of astragaloside Ⅳ in different medicinal parts of Astragalus membranaceus var. mongholicus.Methods The contents of astragaloside Ⅳ in fibrous roots, root heads, taproots and whole roots of A.membranaceus var.mongholicus were determined by HPLC.Results The order of contents of astragaloside Ⅳ in A.membranaceus var.mongholicus was fibrous roots 〉whole roots 〉taproots 〉root heads;The content of astragaloside Ⅳ in A.membranaceus var.mongholicus from Inner Mongolia was 1.85 to 2.7 times of the standard which prescribed in 2010 edition of Chinese Pharmacopoeia.Conclusion Fibrous roots, which were discarded in traditional processing methods, can be used as raw material to extract astragaloside Ⅳ.This study may provide a reference for the harvest and produce of A.membranaceus var.mongholicus.

关 键 词：蒙古黄芪 黄芪甲苷 药用部位 

分 类 号：R284[医药卫生—中药学]