终末期肾病患者心脏瓣膜钙化与冠状动脉钙化进展的关系研究  

The correction of cardiac valve calcification and the progression of coronary artery calcium in end stage renal disease patients

作　　者：王晓春[1] 王泓[1] 戴云[1] 孙晖[1] 李娟[1] 杨斌[1] 

机构地区：[1]南京军区南京总医院超声诊断科,江苏南京210002

出　　处：《东南国防医药》2015年第4期396-398,共3页Military Medical Journal of Southeast China

摘　　要：目的探讨终末期肾病患者心脏瓣膜钙化与冠状动脉钙化进展之间的关系。方法选取127例终末期肾病患者,分析心脏瓣膜钙化与冠状动脉钙化进展的关系。结果终末期肾病患者冠脉钙化在无瓣膜钙化组、主动脉瓣或二尖瓣钙化组、主动脉瓣和二尖瓣同时钙化组中进展的发生率分别为43.1%、71.4%、76.5%(P<0.05)。心脏瓣膜钙化是冠脉钙化进展的独立危险因子。与无瓣膜钙化患者相比,主动脉瓣或二尖瓣钙化患者与主动脉瓣和二尖瓣钙化的终末期肾病患者冠脉钙化积分进展的危险比分别为1.30、1.35(P<0.01)。结论终末期肾病患者心脏瓣膜钙化与冠状动脉的钙化进程密切相关,瓣膜钙化患者冠状动脉钙化的进展更快。Objective To investigate the relationship between cardiac valve calcification and the progression of coronary ar-tery calcium scores（ CACS） in end stage renal disease patients.Methods We collected 127 end stage renal disease patients.Statisti-cal methods were used to analyze the relation between cardiac valve calcification and the progression of coronary calcium.Results In-cidence of the CACS progression in no valve calcification, aortic valve or mitral valve calcification and both valve calcification were 43.1%, 71.4%and 76.5%（P〈0.05）.Cardiac valve calcification was independent risk factor for CAC progression.Patients with aortic valve or mitral valve calcification and both valve calcification had a significantly greater likelihood of increase of CACS （ relative ratios were 1.30,1.35;P〈0.01）.Conclusion The cardiac valve calcification in end stage renal disease patients was strongly asso-ciated with the progression of CACS.CACS progressed rapidly in patients with cardiac valve calcification.

关 键 词：终末期肾病 冠状动脉钙化 心脏瓣膜钙化 进展 

分 类 号：R542.5[医药卫生—心血管疾病] R816.2[医药卫生—内科学]