托烷司琼联合医护一体服务预防乳腺癌根治术后恶心呕吐40例  

Curative Effect Observation of Tropisetron before Radical Mas-Tectomy and Integrated Health Care Services to Prevent Radical Mas-Tectomy Postoperative Nausea and Vomiting in 40 Cases

作　　者：余茹[1] 

机构地区：[1]四川省德阳市人民医院,四川德阳618000

出　　处：《中国药业》2015年第15期82-83,共2页China Pharmaceuticals

摘　　要：目的观察术前给予托烷司琼和医护一体服务预防乳腺癌根治术后恶心呕吐的临床疗效。方法将80例乳腺癌根治术后患者随机分为两组,各40例。对照组于麻醉诱导前静脉缓慢推注平衡液(5 m L)并联合医护一体服务;观察组于麻醉诱导前静脉缓慢推注托烷司琼(0.1 mg/kg)并联合医护一体服务,观察并记录患者行乳腺癌根治术后48 h内恶心、呕吐发生率、程度及不良反应。结果治疗后48 h,对照组、观察组恶心、呕吐发生率为82.50%和45.00%(P<0.05),观察组呕吐频次显著下降,呕吐停止时间显著缩短(P<0.05);两组患者治疗后均出现镇静等轻微不良反应,但未见明显差异。结论术前给予托烷司琼和医护一体服务对预防乳腺癌根治术后恶心、呕吐有显著作用,且未增加不良反应,适合临床推广。Objective To observe the effect of tropisetron before radical mas - tectomy and integrated health care services to prevent breast cancer radical postoperative nausea and vomiting. Methods 80 radical mas - tectomy patients randomly divided into 2 groups, two groups separately 40 patients, patients in control group： received intravenous inject buffer slowly （5 mL） and special management of in-tegrated health care services after operation; and patient in tropisetron group： received intravenous inject tropisetron slowly （0. 1 mg / kg） and special management of integrated health care services after operation, Observe and record the occurrence of PONV and other ad-verse reactions in three groups of patients in 48 h. Results After treatment 48 h, the occurrence rate of PONV in control group and tropisetron group were 82. 50% and 45. 00% （ P〈 0. 05 ）, the frequency of vomiting is decreased in tropisetron group and the vomiting is shorter than control group（ P〈 0. 05）. Patients in both groups after the treatment of mild sedation and other side effects, no signifi-cant difference was not statistically significant. Conclusion The effect of tropisetron before radical mas - tectomy and integrated health care services to prevent breast cancer radical postoperative nausea and vomiting had a significant effects. it is suitable for promotion.

关 键 词：托烷司琼 医护一体式服务 乳腺癌根治术 恶心呕吐 临床疗效 

分 类 号：R969.4[医药卫生—药理学] R975.4[医药卫生—药学]