中西医结合治疗慢性胃溃疡临床研究  

Clinical Study on the Treatment of Chronic Gastric Ulcer by Traditional Chinese Medicine Combined with Western Medicine

作　　者：魏群[1] 魏明[2] 

机构地区：[1]河南中医学院,河南郑州450046 [2]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医学报》2015年第8期1193-1195,共3页Acta Chinese Medicine

基　　金：国家科技部十一五科技支撑计划项目(2007BAI20B094);河南省科技厅科技攻关项目(112102310112)

摘　　要：目的:观察中西医结合的方法治疗慢性胃溃疡的临床疗效。方法:将120例慢性胃溃疡诊断标准患者按随机数字表法(2∶1)分为治疗组80例和对照组40例。对照组采用西医常规治疗,治疗组在对照组治疗基础上加用加减黄芪建中汤治疗。两组共治疗6周,6周后复查胃镜。观察中医证候评分、焦虑自评量表及抑郁自评量表评分、生活质量评分等指标的变化,随访观察0.5 a并统计其复发率。结果:1两组患者临床疗效比较,治疗组明显优于对照组,差异有统计学意义(Z=-8.241,P=0.000)。2治疗后两组患者中医证候评分比较,对照组为(4.17±2.40)分,治疗组为(2.77±2.25)分,差异有统计学意义(P<0.05)。治疗后两组焦虎自评量表及抑郁自评量表评分比较,焦虑自评量表评分对照组为(38.86±6.27)分、(38.52±5.59)分,抑郁自评量表评分治疗组为(35.28±3.67)分、(35.38±5.34)分,差异有统计学意义(P<0.05)。治疗后两组生活质量评分比较,对照组为(70.50±6.57)分,治疗组为(77.35±8.78)分,差异有统计学意义(P<0.05)。结论:中西医结合治疗慢性胃溃疡疗效显著,可改善患者生存质量和焦虑抑郁状态,且不良反应少。Objective：To observe the clinical study on the treatment of chronic gastric ulcer by traditional Chinese medicine （TCM） com- bined with western medicine. Methods ：120 cases were randomly divided into treatment group（40 cases）and control group（ 80 cases）. The control group was given western medicine conventional therapy. The treatment group modified Huangqi Jianzhong Tang based on the control group. One course is 6 weeks, after the one course, gastroscope should be reviewed. Observing TCM syndrome score, anxiety self- assessment scale（SAS） and depression self rating scale（ SDS score） ,the change of the indexes of quality of life score,0.5 -1.0 h and statistics the recurrence rate were followed. Results ： ①Compared with the clinical effects of the patients in the two groups, the treatment group was superior to the control group. The difference was statistically significant （Z = -8. 241, P = 0. 000 ）. ②TCM syndrome score comparison of two groups after treatment showed that the control group was （4.17± 2.40） points, and the treatment group was （2.77± 2.25 ） points, and the difference was statistically significant（ P 〈 0.05 ）. After the treatment, SAS score in the control group was （38.86± 6.27） points, （38.52± 5.59） points, SDS score in the treatment group was （ 35.28±3.67 ） points, （35.38± 5.34 ） points Com- pared with the two groups, the difference was statistically significant （ P 〈 0.05 ）. Compared with the life quality score after the treat- ment, the control group was （70.50 ± 6.57 ） points, the treatment group was （77.35 ± 8.78） points. Compared with the two groups, the difference was statistically significant（ P 〈 0.05 ）. Conclusion： It is remarkable effect for chronic gastric ulcer by TCM combined with western medicine can improve the patients quality of life and anxiety depression, and less adverse reaction.

关 键 词：慢性胃溃疡 中西医结合疗法 脾胃虚寒证 黄芪建中汤 

分 类 号：R259.731[医药卫生—中西医结合]