心包内脂肪与冠状动脉CTA非钙化斑块的相关性  

Association of pericardial fat and noncalcified coronary plaques determined by CTA

作　　者：胡建平[1] 曹代荣[1] 游瑞雄[1] 郑勇[2] 江飞[1] 李秀梅[1] 

机构地区：[1]福建医科大学附属第一医院影像科,福建福州350005 [2]福建医科大学附属第一医院心内科,福建福州350005

出　　处：《中国医学影像技术》2015年第8期1186-1189,共4页Chinese Journal of Medical Imaging Technology

基　　金：福建省教育厅B类科技项目(JB12105)

摘　　要：目的探讨心包内脂肪容积与冠状动脉CTA非钙化斑块的关系。方法连续收集冠状动脉钙化零评分而冠状动脉CTA提示非钙化斑块的患者31例,选取冠状动脉CTA检查正常的患者93例。应用多因素条件Logistic回归分析心包内脂肪容积与非钙化斑块的相关性;采用ROC曲线评估Framingham评分结合心包内脂肪容积对非钙化斑块的预测价值。结果采用多因素条件Logistic回归调整年龄、体质量指数（BMI）、糖尿病、高血压、高脂血症史、吸烟、冠心病家族史影响因子后,心包内脂肪容积与冠状动脉CTA非钙化斑块异常相关（OR=1.23,95%CI 1.09~1.40,P=0.01）。Framingham评分结合心包内脂肪容积较单纯应用Framingham评分对非钙化斑块的预测能力明显提高（Z=2.08,P〈0.05）。结论心包内脂肪容积与非钙化斑块密切相关。Framingham评分结合心包内脂肪容积有助于改善对冠状动脉钙化零评分患者非钙化斑块的预测。Objective To evaluate the relationship between pericardial fat volume （PFV） and noncalcified coronary plaques determined by coronary CTA. Methods Totally 31 cases of zero calcium score and noncalcified coronary plaques diagnosied by CTA, as well as 93 cases with normal coronary CTA results were enrolled. The correlation between PFV and noncalcified coronary plaques was assessed by multivariate conditional Logistic regression analysis. ROC curve was used to evaluate the ability of Framingham score combined with PFV in predicting noncalcified coronary plaques. Results Multiva- riate conditional Logistic regression analysis showed that after adjustment for factors including age, body mass index, hy- pertension, hyperlipidemia, diabetes, smoking and coronary artery disease family history, PFV was significantly associated with patients with noncalcified coronary plaques （OR= 1.23, 95.0%CI 1.09-1.40, P=0.01）. ROC curve analysis showed that compared with simple Framingham score, the ability of PFV combined with Framingham score in predicting noncalcified coronary plaques was significantly improved （Z=2.08, P〈0.05）. Conclusion PFV is significantly related to noncalcified coronary plaques on coronary CTA. Framingham score combined with PFV can improve the prediction of non- calcified coronary plaques in zero calcium score patient.

关 键 词：心包内脂肪 冠状动脉疾病 体层摄影术 X线计算机 

分 类 号：R814.42[医药卫生—影像医学与核医学] R541.4[医药卫生—放射医学]