薜荔茎化学成分的研究  

Chemical constituents from the stems of Ficus pumila

作　　者：肖文琳[1] 陈文豪[1] 宋小平[1] 陈光英[1] 张俊燕[1] 刘丽[1] 韩长日[1] 

机构地区：[1]海南师范大学热带药用植物化学教育部重点实验室,化学与化工学院,海南海口571158

出　　处：《中成药》2015年第8期1734-1737,共4页Chinese Traditional Patent Medicine

基　　金：国家自然科学基金项目(81160391,21362009,81360478);国家国际科技合作专项项目(2014DFA40850)

摘　　要：目的研究薜荔茎的化学成分。方法采用硅胶、Sehadex LH-20、ODS、HPLC等色谱技术进行分离纯化,然后通过理化性质和波谱数据鉴定所得化合物的结构。结果从薜荔茎乙酸乙酯部位中分离得到9个化合物,经鉴定分别为佛手柑内酯(1)、β-谷甾醇(2)、6α-羟基豆甾-4-烯-3-酮(3)、6β-羟基豆甾-4-烯-3-酮(4)、3β-羟基豆甾-5-烯-7-酮(5)、4-acetonyl-3,5-dimerhoxy-p-quinol(6)、胡萝卜苷(7)、柚皮素(8)、金圣草黄素(9)。结论化合物3、4、5和9均为首次从该植物中分离得到,化合物1和6为首次从该属植物中分离得到,并首次对化合物6的碳谱数据进行了归属。AIM To investigate the chemical constituents from the stems of Ficus pumila. METHODS The compounds were isolated by silica gel,Sephadex LH-20,ODS and HPLC column chromatography. Then their structures were elucidated by physicochemical properties and spectral data. RESULTS Nine compounds were isolated and elucidated as bergaten（ 1）,β-sitosterol（ 2）,6α-hydroxystimast-4-ene-3-one（ 3）,6β-hydroxystimast-4-ene-3-one（ 4）,3β-Hydroxysitost-5-en-7-one（ 5）,4-acetonyl-3,5-dimerhoxy-p-quinol（ 6）,daucosterol（ 7）,（ S）-naringenin（ 8） and chrysoeriol（ 9）. CONCLUSION Compounds 3,4,5 and 9 are firstly isolated from this plant. Compounds 1 and 6 are obtained from this genus for the first time,and it is the first time that the13 C spectroscopic data of compounds 6 are identified.

关 键 词：薜荔 茎 化学成分 分离鉴定 

分 类 号：R284.1[医药卫生—中药学]