引种玛卡的抗疲劳实验研究  

Experimental study on anti fatigue effect of the introduced Maca

作　　者：胡远[1] 李兴平[2] 周毅[2] 蒋舜媛[2] 

机构地区：[1]四川省医学科学院四川省人民医院药学部,四川成都610072 [2]四川省中医药科学院,四川成都610041

出　　处：《华西药学杂志》2015年第4期440-441,共2页West China Journal of Pharmaceutical Sciences

基　　金：四川省阿坝州应用技术研究与开发资金项目(2012-01)

摘　　要：目的探讨阿坝州引种玛卡的抗疲劳作用。方法将小鼠随机均分为空白对照组、0.4 g·kg-1人参皂苷组及引种玛卡组(5、2.5、1.25 g·kg-1),ig给药30 d后,检测小鼠的游泳时间、尿素氮、肝糖原和乳酸等指标,统计分析其检测结果。结果引种玛卡和人参皂苷均能明显增加小鼠负重游泳的时间;显著抑制血清尿素氮的升高;显著增加因过度运动所致肝糖原含量的降低;明显地降低过度运动后产生的血乳酸堆积。结论阿坝州引种玛卡有显著抗疲劳的作用。OBJECTIVE To investigate the anti fatigue effect of Maca introduced to Aba. METHODS The mice were randomly allocated into normal control group,ginsenoside 0.4 g·kg^-1 group and 5 g·kg^-1 ,2.5 g·kg^-1, 1.25 g·kg^-1 introduced Maca groups. The corresponding index swimming time of mice, urea mitrogen, hepatic glycogen, and lactic acid was detected ＇,flier intragastric 30 d detection. RESULTS The introduced Maca and ginsenoside could significantly increase the swimming time of weight - loading mice ; and inhibited significantly the increase of serum urea nitrogen. For excessive movement, the consumption of hepatic glycogen content was increased significantly;the blood lactic acid accumulation after overtraining was significantly reduced. CONCLUSION The introduced Maca in Aba Prefecture has significant anti fatigue effect.

关 键 词：玛卡 玛卡独行菜 抗疲劳 游泳时间 实验研究 血清尿素氮 肝糖原 血乳酸堆积 

分 类 号：R96[医药卫生—药理学]