中西医综合治疗活动期类风湿关节炎(湿热内蕴证)临床观察  

T he Observation of Integrated Treatment of Chinese and Western Medicine on the Damp of Active Rheumatoid Arthritis

作　　者：林健祥[1] 曾素娥[1] 李永健[1] 谭朝辉[1] 孙安礼[1] 赵聪玲[1] 

机构地区：[1]广东省江门市新会区人民医院,广东江门529100

出　　处：《中国中医急症》2015年第8期1380-1382,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：广东省江门市科技局立项课题(江科[2014]77号)

摘　　要：目的观察中西医综合治疗活动期类风湿关节炎(RA)(湿热内蕴证)的临床疗效及安全性。方法将60例患者按随机数字表法随机分为两组,治疗组30例,予以口服甲氨喋呤片(MTX),内服二藤蠲痹汤,外敷栀子三黄膏。对照组30例,予以口服MTX。如果两组患者疼痛难忍,予以口服醋氯芬酸片。结果治疗3个月后,治疗组总有效率为83.33%,高于对照组的56.67%(P<0.05);治疗组治疗后晨僵持续时间缩短,休息疼痛程度减轻,肿胀关节数、压痛关节数减少程度均优于对照组(P<0.05);治疗组治疗后血沉(ESR)、C反应蛋白(CRP)、血小板(PLT)均有显著下降,亦优于对照组(P<0.05)。两组均未发生严重不良事件。结论中西医综合治疗活动期RA(湿热内蕴证)具有较好的临床疗效及安全性,疗效优于单独使用MTX。Objective： To observe the clinical efficacy and safety of integrated treatment of Chinese and Western Medicine on The damp of active rheumatoid arthritis. Methods： 60 cases were randomly divided into the control group and the treatment group, 30 cases in each. The treatment group were given oral MTX, the oral Erteng Juanbi Decoction, and the application of Gardenia sanhuang gao,the control group oral MTX. If the pain could be tolerat- ed,oral Aceclofenac Tablets was taken. Results： After 3-month treatment,the total efficacy rate of the treatment group was 83.33%,the control group 56.67%（P〈 0.05）. Compared with the control group,The duration of morning stiffness was shortened;resting pain relieve;the number of Swelling joints and Tenderness joints decreased （P〈 0.05）. ESR,CRP,PLT of the treatment group declined obviously （P〈 0.05）. There was no Adverse events in both groups. Conclusion： The Integrated treatment of Chinese and Western Medicine on The damp of active rheuma- toid arthritis has a good clinical effect and safety, better than using MTX alone.

关 键 词：类风湿关节炎 湿热内蕴 中西医结合疗法 二藤蠲痹汤 栀子三黄膏 

分 类 号：R593.22[医药卫生—内科学]