胸外科患者术后感染病原菌分布与耐药性分析  

Distribution and drug resistance analysis of pathogens causing infections after thoracic surgery

作　　者：栾颖[1] 刘颖[1] 窦海川[1] 邵晓红[1] 许桂红[1] 韩德辉[1] 

机构地区：[1]吉林大学第一医院二部,吉林长春130031

出　　处：《中华医院感染学杂志》2015年第16期3689-3691,共3页Chinese Journal of Nosocomiology

基　　金：吉林省科技厅基金资助项目(20130206027SF)

摘　　要：目的探讨胸外科患者术感染病原菌分布及耐药性,为临床抗菌药物合理应用提供参考依据。方法收集2012年1月-2013年12月胸外科1 416例住院并手术患者临床资料,对术后感染进行统计,分析所检出的病原菌及典型病原菌对临床常用抗菌药物的耐药性,数据采用SPSS 16.0软件进行统计分析。结果胸外科1 416例手术患者中术后发生感染152例,感染率为10.73%;共检出159株病原菌,其中以革兰阴性菌为主,共131株占82.39%;铜绿假单胞菌对青霉素、红霉素、庆大霉素、头孢他啶、氨苄西林耐药,肺炎克雷伯菌对青霉素、红霉素、庆大霉素、头孢他啶耐药,耐药率均>40.00%;金黄色葡萄球菌对青霉素的耐药率较高为80.00%,肺炎链球菌对环丙沙星的耐药率较高为62.50%。结论胸外科术后患者发生感染可延迟预后,临床应合理使用抗菌药物,预防感染,以提高临床治疗效果。OBJECTIVE To discuss the distribution and drug resistance of pathogens causing infections after thoracic surgeries so as to provide references for clinical rational use of antibiotics .METHODS Thoracic surgery patients were collected from Jan .2012 to Dec .2013 to analyze postoperative infections ,pathogenic bacteria distribution , and drug resistance .The pathogens and their drug resistance were analyzed statistically by SPSS 16 .0 software . RESULTS Among the 1 416 thoracic surgery patients who were collected ,152 patients happened postoperative in‐fections ,accounting for 10 .73% ,and 159 strains of pathogenic bacteria were found ,dominating by gram‐negative bacteria with 131 strains ,holding 82 .39% .Pseudomonas aeruginosa showed drug resistance to penicillin ,eryth‐romycin ,gentamicin ,ceftazidime ,and ampicillin .K lebsiella pneumoniae showed drug resistance to penicillin ,e‐rythromycin ,gentamicin ,and ceftazidime .Their drug resistance rates were all over 40 .00% .Staphylococcus au‐reus showed resistant to penicillium with drug resistance rate of 80 .00% .Streptococcus pneumoniae showed drug resistance to ciprofloxacin with rate of 62 .50% .CONCLUSION The incidence of postoperative infections after tho‐racic surgeries would delay prognosis .Antibiotics should be used rationally to prevent infections and improve clini‐cal curative effect .

关 键 词：胸外科 感染 病原菌 耐药性 

分 类 号：R378[医药卫生—病原生物学]