卵泡液总抗氧化能力与体外受精-胚胎移植结局的关系  

The relationship between total antioxidant capacity of follicular fluid and outcomes of in vitro fertilization and embryo transfer

作　　者：朱小凤[1] 莫似恩[1] 黄卡立[1] 孙燕萍[1] 牛向丽[1] 李肖然[1] 柳雪琴[1] 梁志锋[1] 

机构地区：[1]广西壮族自治区人口和计划生育研究中心生殖科,广西南宁530021

出　　处：《中国计划生育和妇产科》2015年第8期49-52,共4页Chinese Journal of Family Planning & Gynecotokology

基　　金：广西人口计划生育科研项目(项目编号:桂人口计生研1006)

摘　　要：目的研究卵泡液总抗氧化能力(total antioxidant capacity,TAC)与体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)结局的关系。方法选取2011年在广西壮族自治区人口和计划生育研究中心行IVF-ET 66例患者资料,按妊娠结局分为妊娠组(28例)和非妊娠组(38例),测定超促排卵后卵泡液TAC,分析其临床妊娠结局与卵泡液TAC之间的关系。结果妊娠组TAC显著高于非妊娠组(P<0.05);两组患者受精率、卵裂率、优质胚胎率等方面比较差异无统计学意义(P>0.05)。结论卵泡液TAC较高者妊娠成功率越高。Objective To investigate the relationship between total antioxidant capacity （TAC） of follicular fluid and the outcomes of in vitro fertilization and embryo transfer （ IVF - ET）. Methods Clinical data of 66 patients underwent IVF - ET in Population and Family Planning Research Center of Guangxi Zhuang Autonomous Region during 2011 were collected. All cases were divided into pregnancy group （ n = 28 ） and non - pregnancy group （ n = 38 ） who were measured the TAC of follicular fluid after controlled ovarian hyperstimulation, the relationship between the clinical pregnancy outcomes and TAC of follicular fluid was analyzed. Results The TAC of pregnancy group was higher than that of non - pregnancy group （ P 〈 0. 05 ）. There was no significant difference in the number of retrieved oocytes, cleavage rate, high - quality embryonic obtained rate between two groups （P 〉 0. 05）. Conclusion Follicular fluid with higher TAC is more helpful to pregnancy.

关 键 词：卵泡液 总抗氧化能力 体外受精-胚胎移植 

分 类 号：R715.2[医药卫生—妇产科学]