RPR和TPPA在梅毒血清测定中的比较研究  

The determination with RPR and TPPA for serum syphilis

作　　者：白艳丽[1] 

机构地区：[1]沈阳市第一人民医院检验科,辽宁沈阳110041

出　　处：《中国医药科学》2015年第1期160-161,200,共3页China Medicine And Pharmacy

摘　　要：目的探讨RPR和TPPA在梅毒血清学测定中的临床价值。方法选择确诊梅毒患者600例,确诊排除梅毒者600例,RPR组使用RPR测定法,TPPA组使用TPPA测定法,比较两组不同阶段梅毒检查阳性率,并分析特异性和敏感性。结果 TPPA组对Ⅰ期、Ⅱ期和Ⅲ期梅毒检查阳性率均显著高于RPR组(P<0.05),TPPA组特异性和敏感性均超过95.0%,显著高于RPR组(P<0.05)。结论 RPR测定其特异性和敏感性低于TPPA检测适用于普查,TPPA检测则可作为确诊方法运用于临床。Objective To explore the clinical value of Rpr and tppa for serum syphilis. Methods 600 cases confirmed with syphilis patients and 600 cases of confirmed without syphilis were choosed, RPR group were used RPR,the TPPA group were used TPPA,then different stage syphilis positive rate of examination and specificity and sensitivity were compared in the two groups. Results TPPA group with stageⅠ, Ⅱ and Ⅲ check syphilis positive rate were significantly higher than RPR group （P〈0.05）, specificity and sensitivity with TPPA group were more than 95.0%,they were higher than RPR group（P〈0.05）. Conclusion The detection of RPR measure with specificity and sensitivity are lower than the TPPA,it is suitable for the census,and TPPA test can be applied to clinical diagnosis method.

关 键 词：快速血浆反应素环状卡片试验 梅毒螺旋体明胶凝集试验 血清测定 

分 类 号：R446.6[医药卫生—诊断学]