2012年哈尔滨市手足口病实验室检测结果分析  

Clinical laboratory testing of hand foot mouth disease in 2012,harbin city

作　　者：张炳丽[1] 宋晓琳[1] 怀清杰[1] 唐道洲[1] 梁爽[1] 王宇[1] 杜溪乔[1] 

机构地区：[1]哈尔滨市疾病预防控制中心,黑龙江哈尔滨150056

出　　处：《中国医药科学》2015年第7期208-210,共3页China Medicine And Pharmacy

摘　　要：目的了解哈尔滨市2012年手足口病病原特点。方法采用Real time RT-PCR对2012年采集的粪便、咽拭子、肛拭子等标本检测肠道病毒、CoxA16、EV71。结果共检测手足口标本1046份,肠道病毒阳性676份（64.6%）,EV71阳性83份（7.9%）,CoxA16阳性489份（46.7%）,其他肠道病毒104份（15.3%）;阳性标本中,男性阳性382份（56.5%）,女性阳性294份（43.5%）;全年6~7月份为高峰,肠道病毒感染主要集中于5岁以下儿童,占阳性标本的89.9%。结论 5岁以下儿童是手足口病感染的主要人群,2012年哈尔滨市手足口主要流行株为CoxA16,而EV71和其他HEV也同时存在。Objective To learn the pathogenic characters of hand-foot- mouth disease（HFMD） in harbin,2012.Methods Stool throal swab and rectal swab samples from patients diagnosed as HFMD were collected to detect pan-enterovirus ,CoxA16 and EV71 by using Real time RT-PCR.Results A total 1046 samples were collected to detect,676 pan-enterovirus positive samples were detected during 2012.Among them,83（7.9%）were EV71, 489（46.7%）were CoxA16,and 104 were the other enterovirus.The positive rate of male was 56.5%,The positive rate of female was 43.5%.Enterovirus infection peaked in June to July.A peak age distribution of enterovirus infection was below five year-old（89.9%）.Conclusion The people who is below five year-old is a peak age distribution of enterovirus infection. CoxA16 is the main pathogen of HFMD in harbin in 2012,EV71 and the other enterovirus are existed at the same time.

关 键 词：手足口病 肠道病毒 COXA16 EV71 

分 类 号：R725.1[医药卫生—儿科]