去白混合浓缩血小板与单采血小板输注临床效果分析  

Clinical effect analysis of eukocyte-deleted mixed platelets and apheresis platelets transfusion

作　　者：林栋[1] 陈宝婵 叶柱江[1] 

机构地区：[1]广东省东莞市中心血站供血服务科,广东东莞523920 [2]广东省东莞市东华医院输血科,广东东莞523000

出　　处：《中国医药科学》2015年第10期198-200,共3页China Medicine And Pharmacy

摘　　要：目的 探讨去白混合浓缩血小板与单采血小板输注的临床效果。 方法 选择2012年10月～2014年10月东华医院收治的需输注血小板的患者200例作为研究对象，随机分为对照组与观察组，对照组应用单采血小板输注，观察组应用去白混合浓缩血小板输注。比较两种血小板质量、两组患者输注效果、临床症状改善情况及不良反应发生情况。 结果 观察组的白细胞残留量低于对照组，差异有统计学意义（ P ＜0.05）。两组患者输注1、24h后的血小板计数均高于输注前，差异有统计学意义（P ＜0.05）；而两组间输注1、24h后血小板计数差异无统计学意义（P ＞0.05）。两组患者组间及组内输注1、24h后的CCI差异无统计学意义（ P ＞0.05），两组输注有效率差异无统计学意义（P ＞0.05）。两组患者输注后止血分数均少于输注前，差异有统计学意义（P ＜0.05）；两组患者不良反应发生率差异无统计学意义（P ＞0.05）。 结论 去白混合浓缩血小板与单采血小板输注效果差异无统计学意义，不良反应率低，值得推广应用。Objective To explore the effect of eukocyte-deleted mixed platelet concentrate and apheresis platelets transfusion. Methods Hospitalized patients required platelet transfusion in Donghua hospital of our city were selected and were group studied.The control group were applied single platelet transfusion, the research group were applied to white mixed concentrated platelet transfusion.Effect of infusion,the improvement of clinical symptoms and adverse effect of the two groups were compared. Results Residual leukocyte of the research group was significantly lower than the control group （P 〈 0.05）.Two groups of patients after 1h and after 24h platelet count were significantly higher than that before infusion （P 〈 0.05）,and the two group after infusion of 1h and 24h among groups after platelet count the difference was not significant （P 〉 0.05）.Two groups of patients between groups and the inner transmission was not statistically significant difference of injection 1h and lost CCI after 24h infusion （P 〉 0.05）.The difference of infusion rate between the two group was not statistically significant （P 〉 0.05）.Two groups of patients after transfusion hemostatic scores were significantly less than before infusion （P 〈 0.05）.The occurrence of two groups of patients with adverse reaction rate has no significant difference （P 〉 0.05）. Conclusion The differences of eukocyte-deleted mixed platelet concentrate transfusion effect and apheresis platelets transfusion effect between the two groups was all not significantly.The rate of adverse reactions is low, it is worthy of popularization and application.

关 键 词：去白混合浓缩血小板 单采血小板 输注 临床效果 

分 类 号：R457[医药卫生—治疗学]