喜炎平联合β-内酰胺类抗生素治疗儿童化脓性扁桃体炎观察  

Clinical Efficacy of Xiyanping Injection Combined with β-lactam Antibiotics in Treatment of Children with Acute Suppurative Tonsillitis

作　　者：乔勇[1] 余霞辉[1] 邓骥[1] 邱有波[1] 舒红文[1] 罗扬[1] 

机构地区：[1]成都市崇州市人民医院儿科,四川成都611230

出　　处：《现代临床医学》2015年第4期258-259,262,共3页Journal of Modern Clinical Medicine

基　　金：四川省成都市科技局科技惠民项目(编号:2013-HM01-3-00004-SF)

摘　　要：目的：探讨喜炎平联合β-内酰胺类抗生素治疗儿童急性化脓性扁桃体炎的临床疗效。方法：将126例儿童急性化脓性扁桃体炎患者随机分为观察组65例与对照组61例。对照组采用β-内酰胺类抗生素治疗，观察组在此基础上加用喜炎平治疗，疗程7～10d，比较2组的临床疗效。结果：观察组临床症状、体征改善时间明显短于对照组（P〈0．05），观察组总有效率高于对照组（P〈0．05）；2组患者不良反应发生率无显著性差异（P〉0．05）。结论：喜炎平联合β-内酰胺类抗生素治疗儿童急性化脓性扁桃体炎，可显著缩短病程，提高治疗有效率，使用安全，值得临床推广。Objective： To explore clinical efficacy of Xiyanping Injection combined with beta- lactam antibiotics in the treatment of children with acute suppurative tonsillitis. Methods： 126 eases of children with acute suppurative tonsillitis were divided randomly into 65 cases of the treatment group and 61 cases of control group. β - lactam antibiotics therapy were used in two groups of children ,but in treatment group added Xiyanping Injection. Therapy time lasted 7 ~ 10 d in two groups. The clinical efficacy was compared in the two groups. Results： Time of clinical symptoms and signs improved in the treatment group was significantly shorter than that in the control group, the difference was statistically significant （ P 〈 0. 05 ）. Total effective rate was 96. 92% in the treatment group, and 85.25% in the control group, the difference was statistically significant （P 〈 0. 05）. The incidence of adverse reaction of the treatment group were 3.08% ,that of the control group were 3.28% ,there was no significant difference in the two groups（ P 〉 0. 05 ）. Conclusion： Xiyanping Injection combined with β -laetam antibiotic in treatment of children with acute suppurative tonsillitis can significantly shorten the course of treatment, improve the treatment efficiency. This method can be used safely, worthy of clinical application.

关 键 词：喜炎平 Β-内酰胺类抗生素 儿童 化脓性扁桃体炎 

分 类 号：R725.6[医药卫生—儿科]