子宫内膜息肉的发病相关高危因素分析  

Analysis of the factors associated with endometrial polyps

作　　者：王群[1] 吴步初[1] 龙雯晴[1] 喇端端[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院妇产科,上海200025

出　　处：《现代妇产科进展》2015年第7期490-492,共3页Progress in Obstetrics and Gynecology

摘　　要：目的：探讨子宫内膜息肉（EPs）发病的相关因素。方法：选取2012年1月至2014年8月在我院妇科微创中心行宫腔镜及病理检查的患者共592例,根据术后病理结果,其中子宫内膜息肉患者385例及非子宫内膜息肉患者207例,分别记录患者临床资料,采用单因素及多因素分析。结果：子宫内膜息肉患者385例（65%）,高发于30~59岁。193例（50.1%）有异常阴道出血,61例为不孕（15.8%）,无症状患者116例（30.1%）。单因素分析发现,年龄、绝经、子宫腺肌症、宫颈息肉、糖尿病、高血压（P〈0.05）是EPs发生的危险因素,产次是EPs发生的保护因素。多因素分析提示,年龄（OR=1.049,95%Cl1.034~1.065,P〈0.001）及子宫腺肌症（OR=2.466,95%Cl1.151~4.012,P〈0.001）为EPs发生的独立危险因素。结论：年龄及子宫腺肌症是子宫内膜息肉发病相关独立危险因素;绝经、宫颈息肉、糖尿病、高血压患者也存在EPs高发的可能,而产次可能是EPs的保护因素。Objective： To explore the factors associated with endometrial polyps （EPs）. Methods： A total of 592 patients were analyzed retrospectively, all patients underwent hysteroscopy and pathological examination during Jan. 2012 to Aug. 2014 at Ruijin Hospital （minimally invasive center for gynecology）. According to the postoperative pathologic results, they were divided into endometrial polyps group and no endometrial polyps group. Univariate and multivariate analysis were performed by professional statistical software SPSS. Results：385 patients（65% ） were diagnosed with EPs,with high incidence in 30 -59 years old group. 193 cases （50.1%） presented with abnormal vaginal bleeding,61 cases of infertility（ 15.8% ） ,116 cases of asymptomatic patients （31. 1% ）. Univariate analysis showed that age, parity, meno- pause, adenomyosis, cervical polyp, diabetes and high blood pressure were statistically associat- ed with endometrial polyps （P〈0.05）. While multivariate logistic regression analysis found a statistically significant association of age （ OR= 1. 049,95% Cl 1. 034 - 1. 065 ,P〈0.001 ） and adenomyosis （ OR = 2. 466,95 % Cl 1.151 - 4.012, P〈0.001 ） with EPs. Conclusion： Age and adenomyosis are independent risk factors for the development of EPs. Besides, postmenopause status, cervicd polyps, diabetes mellitus, hypertension are also high risk factors.

关 键 词：子宫内膜息肉 高危因素 宫腔镜 子宫腺肌症 绝经 

分 类 号：R711[医药卫生—妇产科学]