自体植皮负压封闭引流联合外固定架修复复杂重度开放性肘关节骨折  

Autologous skin grafting, vacuum sealing drainage and external fixation for repair of complex and severe open fracture of the elbow joint

作　　者：汪涛[1] 张弢[1] 冯世庆[1] 郭洪刚[1] 郑永发[1] 

机构地区：[1]天津医科大学总医院骨科,天津市300052

出　　处：《中国组织工程研究》2015年第30期4915-4920,共6页Chinese Journal of Tissue Engineering Research

基　　金：国家自然科学基金项目(81272013)~~

摘　　要：背景:肘关节开放骨折随着工伤事故发生率增高而迅速增高,骨折往往同时伴有严重的软组织损伤。目前采用自体植皮负压封闭引流联合外固定架治疗开放性骨折已被广泛报道。目的:探讨自体植皮负压封闭引流联合外固定架修复复杂重度开放性肘关节骨折的特点。方法:收集天津医科大学总医院骨科2009年1月至2013年12月采用自体植皮负压封闭引流联合外固定架治疗的复杂重度开放性肘关节骨折患者41例,均一期常规清创、外固定架固定并联合负压封闭引流封闭创面,创面有新鲜肉芽组织覆盖后,二期植皮或皮瓣转移修复创面。结果与结论:41例患者随访时间为8-22个月,平均13个月。外固定时间为8-13个月,平均9.8个月。开放性创面Ⅱ期植皮或皮瓣移植手术后均完全愈合。31例患者骨折Ⅰ期愈合,7例延迟愈合,3例不愈合,行髂骨植骨后8-12个月骨折完全愈合。41例重度开放性肘关节骨折患者肢体功能恢复优良率为73%。其中GustiloⅡ型患者肢体功能恢复更佳。提示自体植皮负压封闭引流联合外固定架治疗复杂重度开放性肘关节骨折疗效满意。BACKGROUND：The incidence of open fracture of the elbow joint is increased rapidly with an increased number of accidents. Fractures are often accompanied by severe soft tissue injuries. At present, a combined therapy of autologous skin grafting, vacuum sealing drainage and external fixation for the treatment of open fractures has been widely reported. OBJECTIVE：To investigate the characteristics of the combined therapy of autologous skin grafting, vacuum sealing drainage, and external fixation for repair of complex and severe open fracture of the elbow joint. METHODS：A total of 41 patients with complex and severe open fracture of the elbow joint who received the combined therapy of autologous skin grafting, vacuum sealing drainage and external fixation during January 2009 to December 2013 in General Hospital of Tianjin Medical University, China were selected. Al patients were treated with routine debridement, external fixation and vacuum sealing drainage to cover wound during the first period. During the second period, autologous skin grafting or flap transfer was used to repair wound when the fresh granulation tissue covered the wound. RESULTS AND CONCLUSION：The postoperative folow-up period of these 41 patients was 8-22 months, with an average period of 13 months. External fixation period was 8-13 months with an average period of 9.8 months. The open wounds were completely healed after autologous skin grafting or skin flaps transfer. Fractures were healed in 31 patients during the first period. There were 7 cases of delayed union, 3 cases of nonunion. Al fractures were completely healed during 8-12 months after iliac bone grafting. The excelent and good rate of limb function recovery was 73.1% among 41 patients with severe open fracture of the elbow joint. The limb function of Gustilo II patients better recovered. These results suggest that the clinical effect of the combined therapy of autologous skin grafting, vacuum sealing drainage and external fixation for the treatment of complex and severe open fr

关 键 词：生物材料 材料相容性 外固定架 植皮 负压封闭引流 开放性肘关节骨折 软组织缺损 感染 创面愈合 组织构建 关节活动度 清创 国家自然科学基金 

分 类 号：R318[医药卫生—生物医学工程]