经尿道四区分割法双极等离子体前列腺剜切术治疗良性前列腺增生症术后5年疗效随访  

Efficacy of FPKRP for the treatment of benign prostatic hyperplasia:after 5-year follow-up

作　　者：李磊[1] 吴越[1] 张国飞[1] 邓玮[1] 陈安龙[1] 

机构地区：[1]新疆医科大学第六附属医院泌尿外科,新疆乌鲁木齐830002

出　　处：《现代泌尿外科杂志》2015年第8期550-553,共4页Journal of Modern Urology

基　　金：新疆维吾尔自治区高技术研究发展计划项目基金(No.201110108)

摘　　要：目的探讨经尿道四区分割法双极等离子体前列腺剜切术(FPKRP)治疗良性前列腺增生症(BPH)的疗效及安全性。方法回顾性分析2008年1月至2010年1月新疆医科大学第六附属医院泌尿外科应用FPKRP治疗的BPH患者253例,记录患者术前基本情况、手术操作时间、收获的前列腺组织质量、术后膀胱冲洗时间、住院时间,手术前后国际前列腺症状评分(IPSS)、生活质量评分(QOL)、最大尿流率(Qmax)、残余尿(RUV)的变化。术后随访时间为5年。结果共189例患者获得5年随访。至随访结束,患者平均IPSS、QOL评分、Qmax及RUV较术前均明显改善,差异有统计学意义(P<0.05)。结论 FPKRP治疗BPH具有手术时间短、出血少、不受前列腺大小限制的特点,尤其适用于高龄高危BPH患者;术后3个月患者的排尿症状即可得到明显的解决,且能够在为期5年的长期随访中表现出持久而稳定的疗效,适合在基层医院进行推广。Objective To explore the safety and clinical efficacy of FPKRP for the treatment of benign prostatic hyperplasia （BPH） after 5-year follow-up. Methods Clinical data of 253 BPH cases treated with FPKRP during Jan. 2008 and Jan. 2010 were retrospectively analyzed. Baseline and perioperative data were recorded and analyzed, including age, prostate volume, time when lower urinary tract symptoms occurred, operation time, international prostate symptom score （IPSS） before and after operation, quality of life score （QoL）, maximum urinary flow rate （Qmax）, prostate specific antigen （PSA）, and change of residual urine （RUV）. Results Altogether 189 cases were followed up for 5 years. At the end of follow-up, IPSS, QoL, Qmax and RUV were significantly improved compared with those before operation, and the difference was statistically significant （P〈0.05）. Conclusions The FPKRP has some advantages as shorter operation time, less bleeding and less restriction on the size of prostate. It can be particularly applied to senior and high risk BPH. FPKRP can obviously improve voiding symptoms 3 months after surgery, and the efficacy is stable and sustained throughout the 5-year follow-up. FPKRP is suitable to be spread in grass-roots hospitals.

关 键 词：良性前列腺增生 经尿道前列腺等离子剜切术 前叶 术后 随访研究 

分 类 号：R697.32[医药卫生—泌尿科学] R699.8[医药卫生—外科学]