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作 者:周佳雁[1] 华飞[1] 蒋晓红[1] 任建如[1] 刘震宇[1] 汪心水[1]
机构地区:[1]常州市第一人民医院内分泌科,江苏常州213003
出 处:《常州实用医学》2015年第4期219-222,共4页CHANGZHOU PRACTICAL MEDICINE
摘 要:目的分析2型糖尿病(T2DM)合并非酒精性脂肪肝(NAFLD)的临床特点及寻求早期检测NAFLD的临床手段。方法选择T2DM患者236例,按照是否患有NAFLD分为NAFLD组和非NAFLD组,分析两组基本资料及临床相关参数。结果体重指数(BMI)、舒张压(DP)、胆固醇(TC)、甘油三酯(TO)、低密度胆固醇(LDL-TC)、尿酸(UA)、白细胞计数(WBC)、红细胞计数(RBC)、血红蛋白(Hb)、丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、r谷氨酰转肽酶(r-GGT)NAFLD组明显高于非NAFLD组,病程及年龄NAFLD组明显短或小于非NAFLD组,差异具有统计学意义(P〈0.05)。结论T2DM基础上合并NAFLD将进一步促进代谢紊乱,WBC、RBC、慨、ALT、AST、GGT对检测NAFLD具有一定的临床意义和价值。Objective To investigate the characters of nonalcoholic fatty liver disease( NAFLD) in patients with type 2 di- abetes(T2DM)and find the method to test the NAFLD as early as possible. Methods 236 patients suffer from T2DM were chosen, between them 127 person with NAFLD and 109 without. Contrast the general information and the clinical indexes. Results Pa- tients with NAFLD in T2DM had significant higher body mass index(BMI), diastolic blood pressure(DP), cholesterol(TC), triglyc- eride( TG ), low density lipoproteins ( LDL - TC ), uric acid (UA), white blood cell count ( WBC ), red blood cell cotmt ( RBC ), hemoglobin(Hb), alaninetransarninase(ALT), aspartate aminotransferase(AST) and r - glutmnyl transpeptidase( r - GGT) and lower course of diease, patients' age than those without NAFLD. Conclusion NAFLD could disorder the metabolism of T2DM. WBC, RBC, Hb, ALT, AST and r - GGT may play an important role in the detection of NAFLD.
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