精神科门诊一日精神药物使用情况调查  

PSYCHOTROPICS USE IN OUT- PATIENT CLINIC OF PSYCHIATRY: A SINGLE DAY SURVEY

作　　者：王君[1] 刘秀平[1] 赵晓彦[1] 苏明杰[1] 

机构地区：[1]北京回龙观医院药剂科,北京100096

出　　处：《中国药物依赖性杂志》2015年第4期276-279,共4页Chinese Journal of Drug Dependence

基　　金：北京市医管局重点医学专业发展计划(zylx201409)资助

摘　　要：目的:调查北京回龙观医院门诊患者2015年4月15日精神药物的使用情况。方法:当日精神科门诊患者獉獉獉獉284例,对其使用的抗精神病药、抗抑郁药、心境稳定剂、镇静催眠药/抗焦虑药治疗处方进行调查。结果:(1)当日獉獉284例精神科门诊患者中,男性119例(41.9%),女性165例(58.1%),临床诊断主要为精神分裂症、抑郁症、双相情感障碍、神经症(包括焦虑状态、抑郁状态等)、睡眠障碍、脑器质性障碍等。(2)284例患者中使用1种精神药物治疗的147例(51.76%),使用多种精神药物治疗的131例(46.13%)。抗精神病药使用频率居前3位是喹硫平37例(13.03%)、奥氮平35例(12.32%)、阿立哌唑32例(11.27%)。抗抑郁药使用频率居前3位的是草酸艾司西酞普兰47例(16.55%)、米氮平25例(8.8%)、文拉法辛21例(7.9%)。心境稳定剂使用最多的是丙戊酸钠7例(2.46%)。镇静催眠药/抗焦虑药使用频率居前3位的是马来酸咪达唑仑42例(14.79%)、劳拉西泮31例(10.92%)、佐匹克隆和艾司唑仑各18例(6.34%)。结论:新型非典型抗精神病药和抗抑郁药已经成为精神分裂獉獉症和抑郁症治疗的主要药物,多种精神药物的联用较多,反映出精神药物治疗精神疾病互补增效模式的发展趋势。Objective：To investigate psychotropics use in out - patient of psychiatry in Beijing Huilongguan hospital on April 15, 2015. Methods：A survey in a total of 284 patients in psychiatric clinics was undertaken to determine the use of psychotropics, including antipsychotics, antidepressants, mood stabilizers and hypnotics/anxiolytics. Results： The most common clinical diagnoses were schizophrenia, depression, bipolar disorders, compulsive disorder, neurosis, cerebral disorder, insomnia and anxiety in 284 patients （ 119 males and 165 females）. Among patients, 147（51.76% ） were treated with monotherapy, 131 （46. 13% ） received multiple medications. The most frequently prescribed antipsychotics were quetiapine （37 cases, 13. 03%）, olanzapine （35 cases, 12. 32%）, and aripiprazole （32 cases, 11.27% ）. And the most commonly prescribed antidepressants were escitalopram （47 cases,16.55% ）, mirtazapine （25 cases, 8.8% ）, and venlafaxine （21 cases, 7.9% ）. Mood stabilizers in most frequent use was sodium valproate （7 cases ,2.46% ）. The three frequently prescribed hypnotics/anxiolyties were midazolam （42 cases, 14.79% ）, lorazepam （ 31 cases, 10.92% ）, zopiclone and estazolam （19 cases, 5. 8%） respectively. Conclusion： The novel atypical antipsychotics and antidepressants have become the mainstay for schizophrenia and depression therapy. Common application of multiple medications is indicative of the development trend in psychotropics prescription.

关 键 词：抗精神病药 抗抑郁药 心境稳定剂 镇静催眠药 抗焦虑药 

分 类 号：R971[医药卫生—药品]