缩窄性心包炎患者心包剥脱术疗效研究  被引量:5

Effect of pericardiectomy on constrictive pericarditis patients

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作  者:潘卫军[1] 刘晓红[1] 张冠鑫[1] 韩林[1] 

机构地区:[1]第二军医大学附属长海医院胸心外科,上海200433

出  处:《国际心血管病杂志》2015年第4期282-284,共3页International Journal of Cardiovascular Disease

基  金:国家自然科学基金(81370336)

摘  要:目的:观察心包剥脱术治疗缩窄性心包炎的疗效。方法:收集本院行心包剥脱术治疗的缩窄性心包炎40例患者的临床数据,比较术前、术后的中心静脉压(CVP)、脉压差(DP)、二尖瓣和三尖瓣反流情况,对心脏功能的变化进行回顾性分析。结果:心包剥脱术后患者CVP从术前(20.1±1.0)mmHg明显下降至术后(8.6±0.6)mmHg(P<0.01),DP从术前(28.6±0.8)mmHg上升至术后(47.5±1.3)mmHg(P<0.05),二尖瓣反流血量从术前(2.1±0.36)mL减少至术后(1.0±0.24)mL(P<0.05);三尖瓣反流血量从术前(3.1±0.30)mL减少至术后(1.5±0.26)mL(P<0.001);射血分数和缩短分数无明显变化。结论:心包剥脱术可以降低缩窄性心包炎患者CVP,增加DP,减少心脏瓣膜反流,改善患者生活质量。Objective: To observe the effect of pericardieetomy on constrictive pericarditis treatment. Methods:A total of 40 constrictive pericarditis patients who accepted pericardiectomy were selected in this research. Central venous pressure(CVP), pulse pressure(DP), mitral regurgitation volume(MRV), tricuspid regurgitation volume(TRV) and heart function were measured and analyzed before and after surgery. Results: CVP of constrictive pericarditis patients was (20. 1 ± 1.0) mmHg before and reduced to (8. 6 ±0. 6) mmHg after pericardiectomy (P(0. 01). DP was elevated to (47. 5 ±1.3) mmHg from (28.6 ± 0. 80) mmHg (P〈0. 05). Mitral regurgitation volume was (2. 1 ± 0. 36) mL before and was decreased to (l. 0± 0. 24) mL after surgery (P〈0. 05), while tricuspid regurgitation volume was reduced to (1.5± 0. 26) mL from (3. 1 ±0. 30) mL(P〈0. 001). Both ejection fraction and fractional shortening did not change significantly (P 〉 0. 05 ). Conclusion: Pericardiectomy might reduce CVP, elevated DP, and descent mitral and tricuspid regurgitation volume, which might improve symptom of constrictive pericarditis patients.

关 键 词:缩窄性心包炎 心包剥脱术 中心静脉压 瓣膜反流血量 心脏功能 

分 类 号:R654.2[医药卫生—外科学]

 

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