揉髌手法对兔膝关节骨关节病模型血常规影响的研究  

Effect of Kneading Patella Manipulation on Blood Routine Test of Rabbit Knee Osteoarthritis Model

作　　者：戴七一[1] 黎强[2] 阮萍[1] 覃学流[1] 刘靖[2] 滕居赞[1] 容向宾[1] 韩杰[1] 覃杰[1] 康持 徐通[1] 陈一鑫[1] 

机构地区：[1]广西中医药大学附属瑞康医院,广西南宁530011 [2]广西中医药大学,广西南宁530001

出　　处：《辽宁中医杂志》2015年第8期1564-1566,I0005,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(81260562)

摘　　要：目的:观察揉髌手法对兔膝关节骨关节病模型血常规的影响,进而探讨其治疗的可能作用机制。方法:60只新西兰兔分为手法组、模型组、假模组和正常组各15只。前两组通过手术造成骨内高压型动物模型。造模1周后手法组手法施术5周共17次。造模后12周末分别处置动物,取血检测血常规;膝关节软骨组织评判退变程度,数据经统计学处理。结果:模型组软骨组织退变明显,与手法组比较差异有统计学意义;手法组、模型组、假模组和正常组动物血常规各项指标比较差异无统计学意义。结论:揉髌手法对兔膝关节骨关节病模型血常规的变化无明显影响。Objective：To observe the effect of kneading patella manipulation on the blood routine test of rabbit knee osteoar- thritis model and discuss the possible mechanism action of the treatment. Methods ：60 New Zealand rabbits were randomly divided into four groups：manipulation group,model group,dummy -model group and the normal group, 15 rabbits in each group. A high intraosseous pressure model was established in the manipulation group and model group. A week after modeling, kneading patella manipulation was performed 17 times for each rabbit in the manipulation group in 5 weeks. 12 weeks after modeling,we disposed the animals, taking the blood sampling for routine testing and the knee joint cartilage tissue for detection of degeneration and the data for statistical processing. Results ：The cartilage degeneration in a serious for model group had significant difference compared with that of the manipulation group. There was no significance difference for blood routine test result among all the groups. Conclu- sion：There is no obvious effect of kneading patella manipulation on the blood routine test of rabbit knee osteoarthritis model.

关 键 词：按摩 骨关节病 动物模型 血常规 实验研究 

分 类 号：R684[医药卫生—骨科学]