肠道菌群与肥胖关系的研究进展  

Research progress of the relationship between gut microbiota and obesity

作　　者：陈卫红[1] 苑晓琳 汪云[1] 何丽[1] 

机构地区：[1]中国疾病预防控制中心营养与健康所,北京100050

出　　处：《中国食品卫生杂志》2015年第4期472-475,共4页Chinese Journal of Food Hygiene

摘　　要：肥胖是威胁人类健康的重要慢性病之一,肠道菌群结构失调在其发生、发展中起着重要作用。肠道菌群可促进能量吸收、调控脂肪的合成和储存、诱导机体慢性低度炎症,最终导致肥胖及后续的代谢障碍。阐明肠道菌群与肥胖的关系及作用机制可能会为肥胖的防控与治疗提供新的靶点。Obesity has become one of the important chronic disease which threatens the human health, and gut microbiota play an important role in the occurrence and development of obesity. Proposed mechanisms for the role of gut microbiota include the increase of energy harvest from the diet, regulation synthesis and storage of fat, induction chronic low-grade inflammation, eventually leading to obesity and subsequent metabolism disorders. Elucidating the mechanism of the intestinal flora in obesity may provide new targets for the prevention and treatment of obesity.

关 键 词：肠道菌群 肥胖 能量平衡 慢性低度炎症 

分 类 号：R589.2[医药卫生—内分泌]