扩散张量成像早期诊断慢性压迫性颈髓损伤  

Diffusion Tensor Imaging in Early Diagnosis of Chronic Compressive Cervical Spinal Cord Injury

作　　者：张超[1,2] 穆学涛[1] 马巧稚[1] 钟心[1] 董悦[1] 张雨[1,2] 王宏[1] 

机构地区：[1]武警总医院磁共振科,北京100039 [2]徐州医学院研究生学院,221004

出　　处：《临床放射学杂志》2015年第8期1194-1198,共5页Journal of Clinical Radiology

基　　金：发改办高技【2013】2140号重大灾害医学救援卫星综合应用服务示范基金资助及武警总医院基金项目资助(编号:WZ2012061)

摘　　要：目的探讨3.0 T MR扩散张量成像(DTI)技术对慢性压迫性损伤的早期诊断价值。方法 40例慢性压迫性颈髓损伤患者行常规MRI及DTI检查。实验组分为A1、A2两组,A1组常规MR-T2WI显示颈髓内无异常信号者20例,A2组常规MR-T2WI显示受压部位颈髓出现高信号者20例。选取A1组中非狭窄节段(颈2平面)脊髓作为对照组。分别测量A1、A2及对照组FA值与ADC值,行统计学分析。结果与正常对照组相比,A1组FA值明显降低,ADC值有所升高,结果差异均有显著统计学意义(P<0.05)。与A1组患者相比,A2组FA值进一步明显降低,ADC值显著升高,结果差异均有显著统计学意义(P<0.05)。结论 DTI能够早期发现常规MRI检查不能显示的颈髓异常。Objective To investigate the 3. 0 T MRI DTI diagnostic value in early diagnosis of chronic compressive cervical spinal cord injury. Methods 40 cases of chronic compressive cervical spinal injury patients underwent conventional MRI and DTI scanning with 3. 0T MR. The experimental group was divided into two groups. Group A1 included 20 cases without abnormal signal in spinal cord,and group A2 included equal number showing hyperintense signal in spinal cord compression region. The control group was defined as non-stenotic segment（ C2 level） of spinal cord in group A1. The FA and ADC values of each group were measured and analyzed statistically. Results Compared with control group,FA values of group A1 significantly decreased and there was an increase of ADC values,both of which had statistically difference（ P 〈 0. 05）. Compared with patients of group A1,FA values of group A2 further decreased,while ADC values significantly increased,both of the two results had statistically difference as well（ P 〈 0. 05）. Conclusion DTI may detect early abnormalities in cervical spinal cord that cannot be shown in conventional MRI.

关 键 词：磁共振成像 扩散张量成像 脊髓损伤 

分 类 号：R651.2[医药卫生—外科学] R445.2[医药卫生—临床医学]