良性前列腺增生患者残余尿量与膀胱出口梗阻和逼尿肌收缩力的相关性研究  

The volume of residual urine correlates with bladder outlet obstruction and detrusor contractility in patients with benign prostatic hyperplasia

作　　者：吴伟力[1] 沈华[1] 廖凯[1] 于洪波[1] 周鹤同[1] 吴宏飞[1] 

机构地区：[1]南京明基医院/南京医科大学附属医院泌尿外科,江苏南京210019

出　　处：《中华男科学杂志》2015年第8期729-732,共4页National Journal of Andrology

摘　　要：目的:探讨良性前列腺增生(BPH)患者残余尿量(VRU)与膀胱出口梗阻(BOO)程度和逼尿肌收缩力的相关性。方法:临床诊断为BPH的患者152例,均行B超检查测量前列腺体积(PV)和膀胱VRU,自由尿流率检测,全套尿动力学检查评估BOO程度和逼尿肌收缩力。采用SPSS 20.0统计软件,对B超和尿动力学参数行相关性分析,两样本均数比较采用t检验,定义P<0.05有统计学意义。结果:PV与BOO程度和逼尿肌收缩力有正相关性(相关系数r=0.432和r=0.343,P<0.01)。最大尿流率(Qmax)与BOO程度负相关(r=-0.327,P<0.01),而与逼尿肌收缩力无显著相关性(r=0.123,P>0.05)。VRU≤150 ml时,VRU与逼尿肌收缩力间无显著相关性(r=0.041,P>0.05);当VRU>150 ml时,VRU与逼尿肌收缩力有显著负相关性(r=-0.490,P<0.01);VRU>300 ml时,该相关性尤为明显(r=-0.717,P<0.01)。结论:VRU对逼尿肌功能有一定预测价值。VRU>150 ml者应重视逼尿肌功能的评估,尤其是VRU>300 ml时,建议行尿动力学检查以正确评估BOO程度和逼尿肌收缩力。Objective ： To identify the correlation of the volume of residual urine （VRU） with the severity of bladder outlet obstruction （BOO） and detrusor contractility in patients with benign prostatic hyperplasia （BPH）. Methods： A total of 152 patients with clinically diagnosed BPH underwent ultrasonography for measurement of the prostate volume and RVU, free uroflowmetry, and uro- dynamic examination for the severity of BOO and detrusor contractility. Using the software SPSS20.0, we analyzed the correlation be- tween the ultrasonographic results and urodynamic parameters and compared the two sample means by the t-test. Results： The pros- tate volume was correlated positively with BOO severity （ r = 0. 432, P 〈 0.01 ） and detrusor contractility （ r = 0. 343, P 〈 0.01 ）, while Qmax negatively with BOO severity （ r = 0. 327, P 〈 0.01 ） hut not significantly with detrusor contractility （ r = 0. 123, P 〉 0.05 ）. VRU showed a significantly negative correlation with detrusor contractility when 〉 150 ml （ r = - 0. 490, P 〈 0.01 ） , even more significantly when 〉 300 ml （ r = - 0. 717, P 〈 0.01 ） , but exhibited no significant correlation with it when ≤ 150 ml （ r = 0. 041, P 〉0. 05 ）. Conclusion ： VRU can somehow predict the detrusor function. For patients with VRU 〉 150 ml, especially for those with VRU 〉 300 ml, the detrusor function should be evaluated and urodynamic examination is recommended for exact assessment of BOO severity and detrusor contractility.

关 键 词：良性前列腺增生 残余尿量 膀胱出口梗阻 逼尿肌收缩力 

分 类 号：R697.3[医药卫生—泌尿科学]