舒芬太尼在老年患者麻醉诱导中的临床效果  

Effect of Sulfentanyl on Elderly Patients during General Anesthesia Induction

作　　者：张福清[1] 陈一丽[1] 林钦[1] 

机构地区：[1]福建省肿瘤医院麻醉科,福建福州350014

出　　处：《中国医药指南》2015年第24期31-32,共2页Guide of China Medicine

摘　　要：目的 分析舒芬太尼在老年患者的麻醉诱导时心血管反应的临床效果,对其在麻醉诱导时可行性与安全性进行探讨。方法 从2013年3月至2014年2月手术患者中选择60例ASAⅡ∽Ⅲ级老年患者作为研究对象,并随机分为两组,每组各30例,其中S组使用舒芬太尼诱导插管,F组使用芬太尼进行诱导插管。两组患者均由同一麻醉医师操作,所有患者均分别记录基础值（T0）、插管前1 min（T1）、插管后1 min（T2）和插管后5 min（T3）的收缩压（SP）、舒张压（DP）和心率（HR）,记录不良反应的发生及药物使用情况。结果 S组T1、T2、T3时间点、F组T1、T3时间点SP均显著低于同组T0时间点（P均〈0.05）,二组T1、T3时间点DP均显著低于同组T0时间点（P〈0.05）,F组T2时间点BP显著高于同组T0时间点（P〈0.05）,S组T2时间点BP均显著低于F组同时间点（P〈0.05）。两组T2时间点HR均显著大于同组T0时间点（P〈0.05）。S组在诱导插管时心血管反应明显优于F组。结论 在老年患者的麻醉诱导气管插管中,舒芬太尼比芬太尼更有优势,减轻了气管插管刺激所导致的心血管反应。Objective To analysis the clinical effect of sulfentanyl on elderly patients, and to investigate the feasibility and safety during general anesthesia induction. Methods 60 cases elderly patients with ASAⅡ∽Ⅲ level from March 2013 to February 2014 were selected as the object of study and divided into two groups randomly,there were 30 cases in each group. Sulfentanyl were used in group S and fentanyl were used in group F during general anesthesia induction. The all patients were performed by the same anesthesiologist. All patients were respectively recorded based value（T0）,l rain before intubation（T1）,l min after intubation（T2）and 5 rain after intubation（T3）of SP and DP and HR. The occurrence of adverse reactions and drug use wde also recorded. Results SP at T1 andT2 and T3 time points in group S and SP at T1 and T3 time points in group F significantly lower than that at TO time point（P〈0.05）,DP atT1 and T3 time points in two groups were significantly lower than that at TO time point（P〈0.05）, BP at T2 time of group F was significantly higher than that at the TO time point（P〈O.O5）.BP of group S at T2time point were significantly lower than that of group F at the same time point（P〈0.05）.HR of the two groups at T2 time point were significantly greater than that at the TO time point（P〈0.01）.The cardiovascular response in group S was significantly better than that of in group F.The blood pressure, heart rate and oxygen saturation are more stable. Conclusion Sulfentanyl is more effective than fentanyl in elderly patients during induction of anesthesia, there is less cardiovascular response to the patients during the procedure because of the stimulation of intubation.

关 键 词：舒芬太尼 芬太尼 老年患者 气管内插管 

分 类 号：R614[医药卫生—麻醉学]