不伴有胰高血糖素瘤的坏死松解性游走性红斑2例  

Two Cases of Necrolytic Migratory Erythema without Glucagonoma

作　　者：朱峻[1] 刘泽虎[1] 许爱娥[1] 

机构地区：[1]杭州市第三人民医院,浙江杭州310009

出　　处：《中国皮肤性病学杂志》2015年第9期958-959,980,共3页The Chinese Journal of Dermatovenereology

摘　　要：例1女,43岁;例2男,52岁。临床表现为全身红斑或水疱,反复发作。组织病理检查示:苍白角质形成细胞,上层角质形成细胞坏死。例1胰高血糖素正常,合并胆管癌。例2胰高血糖素升高,合并原发性肝癌,胰尾部囊肿。2例患者均未合并胰高血糖素瘤。One patient was a 43-year-old female and another was a 52-year-old male. Both of them had similar clinical and histopathological features. The skin lesions were superficial migratory erythema and/or vesicles. Histopathology showed upper epidermal necrosis with pale keratinocyte cytoplasm. Fasting plasma gluca- gon level was normal in the female patient with bile carcinoma. Fasting plasma glucagon level was higher in the male patient with primary hepatocarcinoma and pancreas cyst. No glucagonoma were found in both patients.

关 键 词：坏死松解性游走性红斑 胰高血糖素瘤 

分 类 号：R758.61[医药卫生—皮肤病学与性病学]