针灸天枢穴治疗慢性腹泻的系统评价与Meta分析  

Acupuncture ST25 treatment for chronic diarrhea: A Systematic evaluation and Meta analysis

作　　者：秦宗实 刘晓旭[1,2] 刘志顺[1] 

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]北京中医药大学,北京100029

出　　处：《现代中西医结合杂志》2015年第25期2753-2755,2758,共4页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：973计划项目(2011CB505202)

摘　　要：目的系统评价针灸天枢穴治疗慢性腹泻的有效性和安全性。方法电子检索Pub Med、EMBASE、Cochrane Library、日本国立情报研究所(Ci Nii)、中国生物医学文献数据库(CBM)、CNKI、Wan Fang数据库截止2014年12月的针灸天枢穴治疗慢性腹泻的随机对照试验,并对纳入的试验进行Meta分析。结果共纳入4篇文献计403例患者,结果表明针灸天枢穴较旁开针灸非经非穴点缓解慢性腹泻疗效更好[RR=1.80,95%CI(1.51,2.13),P<0.01],针灸天枢穴疗效也优于大横穴[RR=1.42,95%CI(1.10,1.82),P<0.01],但与针灸足三里穴疗效比较差异无统计学意义[RR=1.08,95%CI(0.91,1.28),P=0.39],4篇研究均未提及不良反应。结论针灸天枢穴治疗慢性腹泻有效,并且是相对特异性效应,但证据等级较低。针灸天枢穴治疗慢性腹泻的疗效和安全性还需要更多的高质量随机对照试验和长期的随访研究进一步证实。Object vie It is to assess the therapeutic effect and safety of acupuncture ST 25 treatment for chronic diarrhea with a systematic review.Methods We searched PubMed, EMBASE, Cochrane Library, Citation Information by National In-stitute of Informatics （ CiNii ） , Chinese Biomedical Literature Database （ CBM ） , Wan -Fang Database , China National Knowledge Infrastructure （CNKI）, and from their inception to December 2014.All randomized controlled trials related with acupuncture Tianshu （ST25） for chronic diarrhea were included and meta -analysis would be performed.Results Altogether 4 studies were included, including 403 patients.The result showed that acupuncture Tianshu （ST25） had better effect in global assessment than non -acupuncture points[RR=1.80, 95%CI（1.51,2.13）, P〈0.01], and Daheng （SP15）[RR=1.18, 95%CI（1.01,1.39）, P〈0.01], however there was no difference in the curative effect between Tianshu （ST25） and Tzu-sanli （ST36）[RR=1.08, 95%CI（0.91,1.28）,P=0.39], 4 studies had not mentioned adverse effect .Conclusion Acu-puncture Tianshu ST25 is effect to chronic diarrhea and the it is based on specificity of acupuncture effect , however the degree of evidence is low , more high quality randomized controlled trials related to acupuncture Tianshu ST 25 for chronic diarrhea and long terms follow-up are needed.

关 键 词：针灸 天枢穴 慢性腹泻 系统评价 随机对照试验 

分 类 号：R442.2[医药卫生—诊断学]