基于文献的含阿胶方剂用药规律研究  

Medication Regularity Study on Prescriptions Containing Asini Corii Colla Based on Literature

作　　者：胡永水 嵇传良 张淹 张路 彭照琪 唐仕欢[2] 

机构地区：[1]东阿阿胶股份有限公司国家胶类中药工程技术研究中心,山东聊城252201 [2]中国中医科学院中药研究所,北京100700

出　　处：《中国中医药信息杂志》2015年第9期41-44,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家科技重大专项-重大新药创制(2011ZX09201-201-10);山东省科技计划项目(2013G0031901)

摘　　要：目的探讨含阿胶方剂用药规律,为阿胶临床配伍应用提供数据支撑。方法计算机检索中国知识资源总库(CNKI),检索时间范围1995年1月-2012年12月,共检索到含阿胶方剂文献2635篇;应用中医传承辅助系统(V2.0)软件,采用频次统计和关联规则分析,挖掘文献中含阿胶方剂常用药物频次、主治疾病、主治证候及常用药物核心组合等。结果 2635首含阿胶方剂中,涉及药味1197种,使用频次>200次的药味34种,主治疾病频次>20次的疾病30种,主治证候频次>20次的证候32种;3味药组合频次最高的是甘草、当归、阿胶(486次),4味药组合最高的是白术、阿胶、党参、黄芪(272次)。结论与阿胶配伍用药以补血补气之品居多;主治疾病以妇科疾病居多;主治证候以气血两虚为主。Objective To discuss the medication regularity of prescriptions containing Asini Corii Colla; To provide data support for clinical compatibility application ofAsini Corii Colla. Methods Totally 2635 articles about prescriptions containing Asini Corii Colla were retrieved from CNKI from Jan. 1995 to Dec. 2012. TCM Inheritance Support System V2.0 was employed to conduct frequency analysis and association rules analysis, with a purpose to determine the frequency, indications of disease, indications of syndrome and medicine core combination of common prescriptions containing Asini Corii Colla. Results The 2635 prescriptions containing Asini Corii Colla involved 1197 Chinese herbal medicines, 34 kinds of which were used in extremely high frequency （frequency〉200）. 30 kinds of indications of disease were treated in the high frequency （frequency〉 20）. 32 kinds of indications of syndrome were treated in the high frequency （frequency〉20）. The combination of Glycyrrhizae Radix et Rhizoma, Angelicae Sinensis Radix and Asini Corii Colla showed the highest frequency in all three herbal combinations （486 times）, and Atractylodix Macrocephalae Rhizoma, Asini Corii Colla, Codonopsis Radix and Astragali Radix showed the highest frequency in all four herbal combinations （272 times）. Conclusion Most of compatibility them can enrich blood and tonify qi, and have major functions for gynecological diseases and major syndromes of qi-blood deficiency.

关 键 词：阿胶:配伍应用 主治疾病 主治证候 

分 类 号：R2-05[医药卫生—中医学]