微流控液滴技术及其在生物医学分析中的应用进展  

Microfluidic droplet technology and its application in biomedical analysis

作　　者：贾朋飞[1] 蒋克明[1] 刘聪[1] 周武平[1] 张涛[1] 张志强[1] 黎海文[1] 

机构地区：[1]中国科学院苏州生物医学工程技术研究所,江苏苏州215011

出　　处：《化学研究与应用》2015年第8期1097-1103,共7页Chemical Research and Application

基　　金：中国科学院科研装备研制项目(YZ201444)资助

摘　　要：微流控芯片微滴技术作为一种基于微流控芯片的操控微小体积液体的新技术,以分散的微滴单元作为微反应器,它大大强化了微流控芯片的高灵敏度、低消耗、高通量和自动化等优点,受到日益广泛的重视,并在物理学、化学和生物学等领域中显示出巨大的应用潜力。文章叙述了微流控微滴领域的最新进展,对新的微滴生成技术及操控技术进行介绍,最后阐述了微滴技术在生物医学分析中的最新研究进展。Microdroplet technology is a novel method of fluid manipulation based on Microfluidics that controls droplets with tiny liquid volume. The droplet unit functions as a micro-reactor,which greatly highlights the advantages of microfluidic chip such as high sensitivity, low consumption, high-throughput detection and automation. Due to increasingly widespread attention, microdroplet technology shows great potential applications in the fields of physics, chemistry and biology, etc. Here we briefly review recent advances on microfluidic controls including droplet generation, manipulation and potential applications of microdroplet in biomedical analysis.

关 键 词：微流控系统 微滴生成 微滴操控 生物医学分析 

分 类 号：O657.99[理学—分析化学]