SPE-UPLC-MS/MS测定环境水体中呋喃丹、莠去津、甲萘威及6种邻苯二甲酸酯类  

Determination of Carbofuran,Atrazine,Carbaryl and 6 Kinds of Phthalate Esters(PAEs) in Environmental Water by SPE-UPLC-MS/MS

作　　者：湛社霞[1,2] 匡耀求[1] 李秀英 郭新东 

机构地区：[1]中国科学院广州地球化学研究所,广东广州510640 [2]中国科学院大学,北京100049 [3]广州质量监督检测研究院,广东广州510110

出　　处：《分析测试学报》2015年第8期874-879,共6页Journal of Instrumental Analysis

基　　金：广东省中国科学院全面战略合作项目(2012B090400045)

摘　　要：建立了超高效液相色谱-串联质谱（UPLC-MS/MS）同时测定环境水体中呋喃丹、莠去津、甲萘威和6种邻苯二甲酸酯的分析方法。采用Pak C18固相萃取小柱对样品进行富集和净化,甲醇-水为流动相梯度洗脱,以BEH C18柱分离,在串联质谱的多反应监测模式（MRM）下检测,外标法定量。结果表明,在优化实验条件下,9种目标化合物在0.5-20.0μg/L范围内线性关系良好,相关系数均大于0.998,方法检出限（LOD）和方法定量下限（LOQ）分别为0.05-0.12μg/L和0.2-0.3μg/L,回收率为86.0%-96.5%,相对标准偏差（RSD）小于5%。方法快速准确、回收率高,适用于环境水体中呋喃丹、莠去津、甲萘威及6种邻苯二甲酸酯的测定。An analytical method was developed for the simultaneous determination of carbofuran, atrazine, carbaryl and 6 kinds of phthalate esters（PAEs） in environmental water by ultra performance liquid chromatography coupled with tandem quadrupole mass spectrometry （ UPLC - MS/MS）. The samples were extracted and purified with Pak C18 solid extraction phase（SPE） cartridge. The targeted compounds were separated on BEH C18 column with methanol water solution as mobile phase , determined under multiple reactions monitoring（MRM） mode and quantified by the external standard method. Under the optimized condition, the calibration curves were linear in the range of 0. 5 -20. 0 μg/ L with correlation coefficients larger than 0. 998. The limits of detection （LOD） and the limits of quantitation（LOQ） of the method were in the ranges of 0. 05 -0. 12 μg/L and 0. 2 -0. 3 μg/L, respectively. The recoveries were between 86. 0% and 96. 5% , with RSDs （n = 6） less than 5%. This method was sensitive, accurate and reliable, and was suitable for the determination of carbofuran, atrazine, carbaryl and 6 kinds of phthalate esters（PAEs） in environmental water.

关 键 词：呋喃丹 莠去津 甲萘威 邻苯二甲酸酯 超高效液相色谱-串联质谱法 环境水体 

分 类 号：O657.63[理学—分析化学] F767.2[理学—化学]