拉曼光谱技术及其在药物研究中的应用  

Technologies of Raman spectroscopy and its applications in drug research

作　　者：任小丹[1] 罗香[2] 冯会[1] 衷友泉[1] 尹小英[1] 

机构地区：[1]江西中医药大学药学院,南昌330004 [2]江西省分析测试研究所,南昌330029

出　　处：《中国新药杂志》2015年第16期1851-1855,共5页Chinese Journal of New Drugs

基　　金：国家自然科学基金(81260690)

摘　　要：拉曼光谱因其样品无需特殊前处理,灵敏度较高,操作简单等优点被广泛应用于材料科学、生物医药、环境监测等领域。该技术具有不受水的干扰、可进行活体检测的优势,在药物研究中蕴育着广阔的应用前景。本文概述了拉曼光谱的主要技术原理;探讨了拉曼光谱技术在药物制剂、药物分析、中药鉴定、中药活性成分分析等药物研究领域中的应用。Raman spectra has advantages of high se pre-treatment, thus it is wi ring, and so on. Because prospects in drug research. de of ly used in many fields includin nsitivity, s g materials imple operation and no need of special sample science, biomedicin avoidance from water interference, it can be used in in vivo e, environmental monitodetection, showing good In this paper, we introduced the principles of Raman spectroscopy and the main technologies, and discussed the technologies of Raman spectroscopy in the studies of pharmaceutical preparations, pharma- ceutical analysis, identification medicine and the active ingredient analysis of the traditional Chinese medicine.

关 键 词：拉曼光谱 药物研究 中药研究 

分 类 号：R917[医药卫生—药物分析学]