海南地区无偿献血者抗-HIV阳性结果分析  

Analysis of positive results of HIV antibody in volunteer blood donors in Hainan

作　　者：陈道斌[1] 符慧杰[1] 唐秋萍[1] 

机构地区：[1]海南省血液中心,海南海口570311

出　　处：《中国输血杂志》2015年第7期818-820,共3页Chinese Journal of Blood Transfusion

基　　金：海南省自然科学基金(813268)

摘　　要：目的通过对献血者进行严格的抗-HIV检测,对抗-HIV阳性献血者的人群结构和相关感染途径进行分析,了解献血者HIV的感染状况和流行趋势,为制定降低经输血传播HIV风险的有效措施提供依据。方法献血前在现场进行抗-HIV金标法快速检测,献血后用2家ELISA试剂进行双试剂筛查及NAT筛查,将初筛结果为阳性的样品及时送检确认,对确认阳性者资料进行统计分析。结果本中心2006—2013年无偿献血者抗-HIV筛查检测中,共发现抗-HIV初筛阳性218例,WB确证抗-HIV阳性87例。抗-HIV阳性献血者中,年龄在20—30岁的占59.8%;职业结构中,工人占比率较大(占27.6%);学历结构中,大学专科以上学历占56.3%;性别结构中,男性占89.7%。属固定献血者范畴的有5例。传播途径中,以男男同性性行为为主(MSM),占49.4%,其中年龄在20-29岁29例,共占MSM的67.4%。结论 8年来,本地区无偿献血者抗-HIV阳性率呈上升趋势、且具有年轻化和男性化的特点,传播途径以MSM为主,已经波及固定的无偿献血者队伍,提示在完善血源招募服务工作的同时,加强献血者HIV防护知识的宣教不可忽视。Objective To detect HIV antibody in blood donors,to analyze the prevalence of HIV antibody in population structure,to understand the infection status and popular trends of HIV in blood donors,and to formulate effective measures in order to reduce the risks of HIV transmission by blood transfusion. Methods First,HIV antibody was detected by Gold Standard method for rapid detection before blood donation,then after donation,the blood was detected by two ELISA reagents and NAT screening. Positive specimens from the preliminary screening were sent to be identified in time. Confirmed positive data were statistically analyzed. Results From 2006 to 2013,through HIV antibody screening,218 positive cases were identified in preliminary screening,and of them,87 were confirmed to be positive by WB. Of them,those aged 20 - 30 accounted for 59. 8%. Professionally,27. 6% were workers. Those with college degrees or above accounted for 56. 3% in degree structure. Men accounted for 89. 7% in gender structure,5 cases belonged to the regular blood donors. In pathways,same-sex sexual behavior（ MSM） accounted for 49. 4%,and from those aged 20 to 29,29 cases accounted for 67. 4% among MSM. Conclusion During eight years,the HIV antibody positive rate of voluntary blood donors in Hainan area is on the rise among young people,especially males. MSM was the main pathway. Regular donors had been affected as well. The study prompted an improvement to blood recruitment strategies and strengthening to the educational promotion on HIV protection knowledge among blood donors.

关 键 词：抗-HIV 危险行为 核酸检测 男男同性恋(MSM) 

分 类 号：R446.6[医药卫生—诊断学] R512.91[医药卫生—临床医学]